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Table 3 Frequency of mutations associated with SLDs resistance in MDR MTB isolates

From: Molecular characterization of mutations associated with resistance to second-line tuberculosis drug among multidrug-resistant tuberculosis patients from high prevalence tuberculosis city in Morocco

ATB drug Gene Position Substitution Amino acid change Number of isolates Sub-total Total
FQs gyrA Codon 90 GCG → GTG Ala / Val 2 19 21
GCG → ACG Ala / Thr 2
Codon 91 TCG → CCG Ser / Pro 3
Codon 94 GAC → GCC Asp / Ala 10
GAC → AAC Asp / Asn 1
GAC → CAC Asp / His 1
gyrB 0 0
Aminoglycosides
/cyclic peptides
rrs 0 0
tlyA 0
eis Position 12 C → T 1 2
Position 14 C → T 1