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Table 2 Frequency of mutations identified by sequencing in the rpoB, katG genes, and inhA gene promoter of MTB isolates

From: Molecular characterization of mutations associated with resistance to second-line tuberculosis drug among multidrug-resistant tuberculosis patients from high prevalence tuberculosis city in Morocco

Gene

Position

Type of Mutation

Amino acid change

Number of isolates

Total

rpoB

513

CAA → CCA

Glu / Pro

1

84

513

CAA → CTA

Glu/ Leu

1

516

GAC → GTC

Asp / Val

3

516

GAC → TAC

Asp / Tyr

2

516

GAC → CAC

Asp / His

3

526

CAC → CGC

His / Arg

3

526

CAC → AGC

His / Ser

4

531

TCG → TGG

Ser / Trp

5

531

TCG → TTG

Ser / Leu

62

katG

315

AGC → ACC

Ser / Thr

81

inhA promoter

-15

C → T

 

3