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Table 3 Predictors for ARTI-attributable hospital admission among all immunocompromised patients and stratified by age-groups (adults vs children)

From: Burden of severe RSV disease among immunocompromised children and adults: a 10 year retrospective study

N = 215 (152 adults, 63 children)a Univariable analyses Multivariable analyses
OR (95% CI) OR (95% CI) P value
Increasing age (by 10Y range) All 1.0 (0.9;1.1) 1.0 (0.9;1.2) 0.558
Adults 1.6 (1.3;2.1) 1.4 (1.0;1.8) 0.027
Children 0.6 (0.2;1.8)
Bacterial co-infection All 1.6 (0.8;3.4) 1.5 (0.7;3.3) 0.340
Adults 2.2 (0.9;5.2) 1.7 (0.6;4.5) 0.286
Children 0.8 (0.2;3.3) 1.0 (0.2;4.6) 0.995
ALC All 1.0 (1.0;1.2) 1.0 (1.0;1.2) 0.420
Adults 1.0 (1.0;1.2) 1.0 (1.0;1.2) 0.436
Children 0.8 (0.5;1.2) 0.8 (0.5;1.2) 0.309
SOT All 2.1 (0.9;5.1) 1.9 (0.8;4.6) 0.166
Adults 2.1 (0.9;5.4) 1.6 (0.6;4.4) 0.312
Children 1.7 (0.1;53.3)
Leukemia/lymphoma All 4.0 (1.7;9.5) 3.9 (1.7;9.7) 0.002
Adults 3.0 (1.0;9.3) 1.5 (0.4;5.2) 0.556
Children 7.5(1.1;149.7)
Solid tumor All 7.2 (2.6;21.2) 7.4 (2.7;21.9) < 0.001
Adults 7.4 (2.1;28.4) 5.2 (1.4;20.9) 0.015
Children 10.5 (1.2;240.1)
Chronic immunosuppressive medication All 10.5 (3.7;32.9) 9.5 (3.3;30.2) < 0.001
Adults 8.2 (2.6;28.4) 4.1 (1.1;16.0) 0.034
Children 35.0 (2.6;1450.5)
PID All 4.3 (0.7–26.1) 4.5 (0.7;29.0) 0.097
Children 10.5 (0.8–298.2)
  1. Absolute lymphocyte counts (ALC), Hematopoietic stem cell recipients (HSCT), Primary immunodeficiency disease (PID) Solid organ transplant (SOT), Acute-respiratory-tract infection (ARTI)
  2. aN refers to the total number of patients included in all multivariable analyses for whom information on all predictors and outcomes were available. 24 patients (23 adults – 1 child) were excluded from univariable and multivariable analyses because of missing values for nALC
  3. Limited sample size in the pediatric subset limited the number of predictors, which could be included in multivariable analyses (−)