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Table 5 Summary of possible algorithms with a performance as good as or better than the current algorithm ranked in order of costa

From: Evaluation of HIV-1 rapid tests and identification of alternative testing algorithms for use in Uganda

Rank Screening Confirmatory Tie Breaker Sensitivity Specificity PPV NPV FPR FNR Cost per test ($)
1b Determine SD Bioline StatPak 99.2 99.1 99 99.2 0.9 0.8 1.43
2 Determine Medinostics Statpak 99.1 99.2 99.2 99.1 0.8 0.9 1.43
3b Determine Statpak SD Bioline 99.2 99.1 99 99.2 0.9 0.8 1.43
4 Determine StatPak Medinostics 99.1 99.2 99.2 99.1 0.8 0.9 1.43
5c Determine Statpak Unigold 99.1 98.9 98.9 99.1 1.1 0.9 1.50
6 Determine Unigold Statpak 99.1 98.9 98.9 99.1 1.1 0.9 1.54
7 Determine SD Bioline Insti 99.1 99.0 99.0 99.1 1.0 0.9 1.78
8 Determine Medinostics Insti 99.1 99.1 99.1 99.1 0.9 0.9 1.78
9b Determine Statpak Insti 99.2 99.1 99.0 99.2 0.9 0.8 1.79
10 Determine Unigold Insti 99.1 98.9 98.9 99.1 1.1 0.9 1.89
11 Determine Insti Medinostics 99.1 99.1 99.1 99.1 0.9 0.9 2.05
12 Determine Insti SD Bioline 99.1 99.0 99.0 99.1 1.0 0.9 2.05
13 Determine Insti StatPak 99.2 99.1 99.0 99.2 0.9 0.8 2.05
14 Determine Insti Unigold 99.1 98.9 98.9 99.1 1.1 0.9 2.11
15 Insti SD Bioline Medinostics 99.1 99.4 99.4 99.1 0.6 0.9 4.61
16 Insti Medinostics SD Bioline 99.1 99.4 99.4 99.1 0.6 0.9 4.61
17 Insti SD Bioline StatPak 99.2 99.4 99.4 99.2 0.6 0.8 4.61
18 Insti Medinostics Statpak 99.1 99.4 99.4 99.1 0.6 0.9 4.61
19 Insti Statpak SD Bioline 99.2 99.4 99.4 99.2 0.6 0.8 4.61
20 Insti StatPak Medinostics 99.1 99.4 99.4 99.1 0.6 0.9 4.61
21 Insti Statpak Unigold 99.1 99.4 99.3 99.1 0.6 0.9 4.62
22 Insti Unigold Statpak 99.1 99.4 99.3 99.1 0.6 0.9 4.66
  1. aThe order of ranking followed the priority of: 1- Cost, 2-sensitivity, 3-specificity, 4-PPV, 5-NPV, 6-FPR, 7-FNR; b In bold are the proposed algorithms;
  2. cIn italics current algorithm