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Table 4 risk factors for receiving an inadequately dosed FQ prescription

From: Systemic fluoroquinolone prescriptions for hospitalized children in Belgium, results of a multicenter retrospective drug utilization study

 

Unadjusted Odds Ratio

Adjusted Odds Ratio

Age

  < 1 years

0.249 (0.092–0.658) p = 0.005

0.263 (0.097–0.701) p = 0.008

 1–3 years

0.447 (0.198–0.976) p = 0.046

0.467 (0.206–1.027) p = 0.062

 3–6 years

0.269 (0.113–0.622) p = 0.002

0.254 (0.106–0.588) p = 0.020

 6–12 years

0.672 (0.281–1.605) p = 0.368

0.702 (0.292–1.684) p = 0.425

 12–18 years

- (reference category)

- (reference category)

 CF vs. non-CF

1.332 (0.398–3.992) p = 0.618

 IV vs. orally

0.816 (0.480–1.384) p = 0.451

 Study center

1.294 (0.753–2.253) p = 0.356

 Off-label vs. on-label indication

0.780 (0.357–1.597) p = 0.512

 Culture absent vs. present

1.292 (0.744–2.226) p = 0.358

 Other FQ vs. ciprofloxacin

3.566 (0.638–66.71) p = 0.234

2.601 (0.436–49.86) p = 0.382

Department

 Academic pediatrics ward

1.238 (0.686–2.248) p = 0.479

 

 Oncology

1.213 (0.595–2.549) p = 0.601

 

 PICU

- (reference category)