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Table 1 recommended doses of systemic FQ in the study centers

From: Systemic fluoroquinolone prescriptions for hospitalized children in Belgium, results of a multicenter retrospective drug utilization study

FQ

Adequate oral dose

Adequate intravenous dose

Ciprofloxacin

non-CF: 20–30 mg/kg/day in 2 doses, max. 500 mg/dose.

CF: 40 mg/kg/day in 2 doses, max. 750 mg/dose

non-CF: 20–30 mg/kg/day in 2–3 doses, max. 400 mg/dose.

CF: 30–40 mg/kg/day in 2–3 doses, max. 1200 mg/day.

Moxifloxacin

10 mg/kg/day in one dose, max. 400 mg/dose.

Levofloxacin

<  5 years: 20 mg/kg/day in 2 doses, max. 1000 mg/day.

>  5 years: 10 mg/kg/day in 1 dose, max. 1000 mg/day.

Norfloxacin

Therapeutic indications: 10 mg/kg/day in one dose, max. 400 mg/dose.

Prophylactic indications: 2–5 mg/kg/day in 2 doses, max. 400 mg/dose.