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Table 1 Participant characteristics, comparing MTB-culture positives and negatives

From: Performance of loop-mediated isothermal amplification assay in the diagnosis of pulmonary tuberculosis in a high prevalence TB/HIV rural setting in Uganda

Demographic and clinical characteristics Total, N = 233 Frequency (%) MTB Culture positive, N = 83 MTB Culture negative, N = 150 P value
Hospital setting 126 (54.1) 37 (44.5) 89 (59.3) 0.030
Median age, years (IQR) 40 (30–53) 38 (27-46) 41 (30-55) 0.240
Median time to LAMP testing, hours (IQR) 5 (4-6) 5 (5-6) 5 (4-6) 0.300
Gender
 Male 129 (55.4) 52 (62.7) 77 (51.3) 0.096
 Female 104 (44.6) 31 (37.3) 73 (48.7)  
Cough for 2 weeks 232 (99.6) 83 (100) 149 (99.3) 1.000
Bloody sputum 34 (14.6) 12 (14.5) 22 (14.7) 0.966
Fever for 2 weeks 207 (88.8) 74 (89.2) 133 (88.7) 0.909
Night sweats for 2 weeks 180 (77.3) 67 (80.7) 113 (75.3) 0.347
TB treatment history
 Previous TB treatment 23 (9.9) 9 (10.8) 14 (9.3) 0.711
 New TB treatment 210 (90.1) 74 (89.2) 136 (90.7)  
HIV co-infected 113 (48.5) 44 (53.0) 69 (46.0) 0.305
ART (N = 113) 63 (55.8) 23 (52.3) 40 (58.0) 0.552
Weight loss in 1 month 188 (81.0) 68 (81.9) 120 (80.5) 0.796
Smear microscopy
 Positive for AFB 43 (18.5) 38 (45.8) 5 (3.3) 0.000
  3+ (>  250 AFB in one field) 14 14 0  
  2+ (25-250 AFB in one field) 13 12 01  
  1+ (3-24 AFB in one field) 13 11 01  
  Scanty (5-49 AFB in one length) 03 03 0  
Negative for AFB 190 (81.6) 45 (54.2) 145 (96.7)  
TB-LAMP
 Positive 49 (21.0) 46 (55.4) 03 (2) 0.000
 Negative 184 (79) 37 (44.6) 147 (98)  
  1. IQR Interquartile range, ART Antiretroviral therapy, AFB Acid Fast Bacilli