Table 1 Participant characteristics, comparing MTB-culture positives and negatives
Demographic and clinical characteristics | Total, N = 233 Frequency (%) | MTB Culture positive, N = 83 | MTB Culture negative, N = 150 | P value |
|---|---|---|---|---|
Hospital setting | 126 (54.1) | 37 (44.5) | 89 (59.3) | 0.030 |
Median age, years (IQR) | 40 (30–53) | 38 (27-46) | 41 (30-55) | 0.240 |
Median time to LAMP testing, hours (IQR) | 5 (4-6) | 5 (5-6) | 5 (4-6) | 0.300 |
Gender | ||||
Male | 129 (55.4) | 52 (62.7) | 77 (51.3) | 0.096 |
Female | 104 (44.6) | 31 (37.3) | 73 (48.7) | |
Cough for 2 weeks | 232 (99.6) | 83 (100) | 149 (99.3) | 1.000 |
Bloody sputum | 34 (14.6) | 12 (14.5) | 22 (14.7) | 0.966 |
Fever for 2 weeks | 207 (88.8) | 74 (89.2) | 133 (88.7) | 0.909 |
Night sweats for 2 weeks | 180 (77.3) | 67 (80.7) | 113 (75.3) | 0.347 |
TB treatment history | ||||
Previous TB treatment | 23 (9.9) | 9 (10.8) | 14 (9.3) | 0.711 |
New TB treatment | 210 (90.1) | 74 (89.2) | 136 (90.7) | |
HIV co-infected | 113 (48.5) | 44 (53.0) | 69 (46.0) | 0.305 |
ART (N = 113) | 63 (55.8) | 23 (52.3) | 40 (58.0) | 0.552 |
Weight loss in 1 month | 188 (81.0) | 68 (81.9) | 120 (80.5) | 0.796 |
Smear microscopy | ||||
Positive for AFB | 43 (18.5) | 38 (45.8) | 5 (3.3) | 0.000 |
3+ (> 250 AFB in one field) | 14 | 14 | 0 | |
2+ (25-250 AFB in one field) | 13 | 12 | 01 | |
1+ (3-24 AFB in one field) | 13 | 11 | 01 | |
Scanty (5-49 AFB in one length) | 03 | 03 | 0 | |
Negative for AFB | 190 (81.6) | 45 (54.2) | 145 (96.7) | |
TB-LAMP | ||||
Positive | 49 (21.0) | 46 (55.4) | 03 (2) | 0.000 |
Negative | 184 (79) | 37 (44.6) | 147 (98) | |