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Fig. 8 | BMC Infectious Diseases

Fig. 8

From: IL-10+ NK and TGF-β+ NK cells play negative regulatory roles in HIV infection

Fig. 8

Effects of rIL-10 and rTGF-β on perforin release by NK cells

PBMCs were co-cultured with rIL-10 and/or rTGF-β for 5 h, and then stimulated with PMA and ionomycin for 6 h. The inhibition of perforin release by NK cells by different concentrations of rIL-10 (a) or rTGF-β (b) was determined. The effects of treatment with both rIL-10 and rTGF-β on perforin release by NK cells were synergistic (c)

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