Fig. 6
From: IL-10+ NK and TGF-β+ NK cells play negative regulatory roles in HIV infection
Effect of rIL-10 and rTGF-β on IFN-γ secretion by NK cells
PBMCs were co-cultured with rIL-10 and/or rTGF-β for 5 h, then stimulated with rIL-12 and rIL-15 for 24 h. Representative flow-cytometry plots demonstrated the effect of rIL-10 or rTGF-β on IFN-γ secretion by NK cells (a). IFN-γ secretion by NK cells was inhibited by different concentrations of rIL-10 (b) or rTGF-β (c) and synergistically by treatment with both rIL-10 and rTGF-β (d)