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Table 2 Bivariate analysis of risk factors for mortality at 30 days following the diagnosis on ICU

From: Outcome and prognostic factors of patients with right-sided infective endocarditis requiring intensive care unit admission

Factor Survivors n = 29 Non survivors n = 8 p
Gender, Male/Female 17/12 3/5 0.28
Mean Age 44.8 ± 16.5 67.2 ± 14.1 <  0.004
Age > 45 years 12 (41.3) 8 (100) <  0.004
Cause of ICU admission
 Septic shock 7 (24.1) 2 (25) = 0.9
 Cardiac failure 9 (31) 2 (25) = 0.7
 Respiratory failure 11 (37.9) 1 (12.5) = 0.18
 Renal failure 2 (6.9) 2 (25) = 0.14
 Other causes 0 (0) 1 (12.5)  
Mean SAPS II 29.6 ± 14.8 42.5 ± 22.9 = 0.12
Mean SOFA 5.9 ± 4.2 7.6 ± 5.0 = 0.39
Charlson score 2.5 ± 3.3 4.8 ± 3.3 <  0.05
Charlson score > 3 10 (34.5) 6 (75) <  0.05
Diagnosis before ICU admission 12 (41.3) 0 (0) <  0.03
RSIE acquired in ICU 2 (6.9) 1(12.5) = 0.6
Community-acquired RSIE 12 (41.4) 6 (75) = 0.09
Nosocomial endocarditis 10 (34.5) 4 (50) = 0.42
ICED associated endocarditis 2 (6.9) 2 (25) = 0.14
Source of infection
 cutaneous 4 (13.8) 3 (37.5) = 0.12
 IVDA 8 (27.6) 0 (0) = 0.09
 Catheter related infection 9 (31) 1 (12.5) = 0.28
 unknown 6 (20.7) 1 (12.5) = 0.6
 other 0 (0) 1 (12.5) = 0.05
Native tricuspid valve endocarditis 28 (96.6) 7 (87.5) = 0.31
Severe tricuspid regurgitation 9 (31) 2 (25) = 0.74
Vegetation size 19.0 ± 9.7 23.0 ± 13.9 = 0.59
LVEF < 50% 6 (20.7) 2 (25) = 0.79
Neurological complications 3 (10.3) 2 (25) <  0.02
Septic pulmonary embolism (n = 30)* 23/26 (88.6) 1/4 (25) <  0.002
Pathogens
 Methicillin-sensible S. aureus 15 (51.7) 2 (25) = 0.2
 Methicillin-resistant S. Aureus 6 (20.7) 3 (37.5) = 0.27
 Fungal 2 (6.9) 2 (25) = 0.12
 Other pathogens 8 (27.6) 0 (0) = 0.09
Aminoglycosides indication (n = 34)** 27/28 5/6 = 0.23
Aminoglycosides delivery (n = 34)** 22/28 2/6 <  0.05
Aminoglycosides conformity(n = 34)** 21/28 1/6 <  0.02
Surgical indication 12 (41.4) 2 (25) = 0.39
 Indication: size of vegetation 9 (31) 2 (25) = 0.42
 Indication: RHF 6 (20.7) 2 (25) = 0.18
 Two indications 3 (10.3) 2 (25) <  0.05
Surgical procedure performed 13 (44.8) 1 (12.5) = 0.09
  1. Data are presented as No (%)
  2. * CT scan has not been performed for seven patients
  3. ** No Evaluation could be made for 3 patients