Late presentation for HIV care in Southwest Ethiopia in 2003–2015: prevalence, trend, outcomes and risk factors

BMC Infectious Diseases

Table 1 Measurements for late presentation for HIV care (LP)

Adults	Late presentation for HIV care [6, 35]^a
	Enrolled in 2003–11	Enrolled in 2012–15
	CD4 lymphocyte count of < 200 cells/ μl irrespective of WHO clinical stage at the time of first presentation to the HIV care	CD4 lymphocyte count of < 350 cells/ μl irrespective of WHO clinical stage at the time of first presentation to the HIV care
	WHO clinical stage 3 or 4 irrespective of CD4 count at the time of first presentation to the HIV care ^b	WHO clinical stage 3 or 4 irrespective of CD4 count at the time of first presentation to the HIV care
Children^c	Late presentation for HIV care [70]
		Moderate immune-suppression (damage) if CD4 count between	Severe immune-suppression (damage) if CD4 count between
	0–12 months	750–1500 cells/ μl	< 750 cells/ μl
	1–5 years	500–1000 cells/ μl	< 500 cells/ μl
	≥ 6 years	200–500 cells/ μl (enrolled in 2003–2011)	< 200 cells/ μl (enrolled in 2003–11)
	≥ 6 years	350–500 cells/ μl (enrolled in 2012–2015)	< 350 cells/ μl (enrolled in 2012–2015)

ART: antiretroviral therapy; CD4: cluster for differentiation 4; WHO: World Health Organization; Tb: Tuberculosis; PCP: pneumocystis carinii (juvenii) pneumonia
^aThe definition for LP among Tb/HIV co-infected population was only based on the CD4 criteria [4]
^bWHO clinical Stage 3was defined if one of the following is present in an HIV diagnosed patient: weight loss of > 10% body weight, chronic diarrhea for > 1 month, fever for > 1 month, oral candidiasis, oral hairy leukoplakia, or pulmonary Tb within the previous year, or severe bacterial infections; WHO clinical Stage 4 was defined if one of the following is present in an HIV diagnosed patient: HIV wasting syndrome, PCP, toxoplasmosis of the brain, cryptosporidiosis or isosporiasis with diarrhea for > 1 month, cytomegalovirus disease of an organ other than liver, spleen or lymph node, herpes simplex virus infection, progressive multifocal leukoencephalopathy, candidiasis, extra-pulmonary Tb, lymphoma, kaposi’s sarcoma, HIV encephalopathy
^cLP is also defined if WHO clinical stage 3 or 4 at first visit to the ART clinics

ISSN: 1471-2334