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Table 2 Distribution of characteristics of TB patients according to their M. tuberculosis isolates’ IS6110 RFLP cluster size

From: Risk factors associated with cluster size of Mycobacterium tuberculosis (Mtb) of different RFLP lineages in Brazil

   

cluster size

Characteristics

Categories

All patients

PUa

2–5

6–9

≥ 10

  

N = 959

(%)

N = 498

(%)

N = 266

(%)

N = 87

(%)

N = 108

(%)

Demographic

 Age (years old)

< 20 years

100

(11.0)

38

(8.0)

36

(14.6)

17

(19.8)

9

(9.1)

21–30 years

247

(27.3)

132

(27.9)

60

(24.4)

25

(29.1)

30

(30.3)

31–40 years

220

(24.4)

120

(25.4)

50

(20.3)

23

(26.7)

27

(27.3)

41–50 years

194

(21.4)

101

(21.4)

60

(24.4)

14

(16.3)

19

(19.2)

> 50 years

143

(15.8)

82

(17.4)

40

(16.3)

7

(8.2)

14

(14.4)

 Gender

Female

287

(30.0)

153

(31.0)

81

(30.0)

24

(28.0)

29

(27.0)

Male

672

(70.0)

345

(69.0)

185

(70.0)

63

(72.0)

79

(73.0)

 Race

White

190

(30.0)

100

(31.0)

56

(32.0)

20

(31.0)

14

(19.0)

Black

119

(19.0)

55

(17.0)

30

(17.0)

14

(22.0)

20

(27.0)

Othersb

323

(51.0)

165

(52.0)

89

(51.0)

30

(47.0)

39

(53.0)

 School Level (years)

≤ 4 years

106

(21.0)

56

(22.0)

32

(23.0)

10

(20.0)

8

(16.0)

5–8 years

304

(61.0)

154

(59.0)

86

(61.0)

30

(61.0)

34

(67.0)

≥ 8 years

90

(18.0)

49

(19.0)

23

(16.0)

9

(18.0)

9

(18.0)

 Metropolitan Area

Vitória

583

(61.0)

293

(59.0)

162

(61.0)

63

(72.0)

65

(60.0)

Vila Velha

89

(9.0)

49

(10.0)

25

(9.0)

7

(8.0)

8

(7.0)

Cariacica

120

(13.0)

60

(12.0)

34

(13.0)

9

(10.0)

17

(16.0)

Serra

123

(13.0)

70

(14.0)

36

(14.0)

4

(5.0)

13

(12.0)

Others

44

(5.0)

26

(5.0)

9

(3.0)

4

(5.0)

5

(5.0)

Clinical

 X Ray

No

46

(6.0)

20

(5.0)

17

(9.0)

3

(4.0)

6

(7.0)

Yes

667

(94.0)

349

(95.0)

178

(91.0)

65

(96.0)

75

(93.0)

 TB Presentation

PTBc

779

(81.0)

389

(78.0)

217

(82.0)

79

(91.0)

94

(87.0)

EPTB

111

(12.0)

71

(14.0)

26

(10.0)

6

(7.0)

8

(7.0)

PTB + EPTB

69

(7.0)

38

(8.0)

23

(9.0)

2

(2.0)

6

(6.0)

 AFB Smears Results

Negative

147

(15.0)

82

(17.0)

48

(18.0)

6

(7.0)

11

(10.0)

Positived

802

(85.0)

413

(83.0)

214

(82.0)

81

(93.0)

94

(90.0)

Molecular

 Spoligotyping

Non LAM

412

(48.0)

217

(46.0)

144

(61.0)

33

(47.0)

18

(22.0)

LAM

448

(52.0)

255

(54.0)

91

(39.0)

37

(53.0)

65

(78.0)

 RDRio Genotype

Non RDRio

552

(60.0)

299

(62.0)

182

(70.0)

36

(50.0)

35

(33.0)

RDRio

369

(40.0)

184

(38.0)

78

(30.0)

36

(50.0)

71

(77.0)

  1. a – When the unique patterns (PU) were the reference group and were compared with all others genotyped TB cases by
  2. cluster size in number of patients per cluster
  3. b – Based on the SINAN response field for skin colour
  4. c– PTB = pulmonary TB, EPTB = extrapulmonary TB
  5. d- All smear positive results were stratified as + 1 (10–99 AFB/100 fields), + 2 (1–10 AFB/field) and + 3 (> AFB/field)