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Table 2 Distribution of characteristics of TB patients according to their M. tuberculosis isolates’ IS6110 RFLP cluster size

From: Risk factors associated with cluster size of Mycobacterium tuberculosis (Mtb) of different RFLP lineages in Brazil

    cluster size
Characteristics Categories All patients PUa 2–5 6–9 ≥ 10
   N = 959 (%) N = 498 (%) N = 266 (%) N = 87 (%) N = 108 (%)
Demographic
 Age (years old) < 20 years 100 (11.0) 38 (8.0) 36 (14.6) 17 (19.8) 9 (9.1)
21–30 years 247 (27.3) 132 (27.9) 60 (24.4) 25 (29.1) 30 (30.3)
31–40 years 220 (24.4) 120 (25.4) 50 (20.3) 23 (26.7) 27 (27.3)
41–50 years 194 (21.4) 101 (21.4) 60 (24.4) 14 (16.3) 19 (19.2)
> 50 years 143 (15.8) 82 (17.4) 40 (16.3) 7 (8.2) 14 (14.4)
 Gender Female 287 (30.0) 153 (31.0) 81 (30.0) 24 (28.0) 29 (27.0)
Male 672 (70.0) 345 (69.0) 185 (70.0) 63 (72.0) 79 (73.0)
 Race White 190 (30.0) 100 (31.0) 56 (32.0) 20 (31.0) 14 (19.0)
Black 119 (19.0) 55 (17.0) 30 (17.0) 14 (22.0) 20 (27.0)
Othersb 323 (51.0) 165 (52.0) 89 (51.0) 30 (47.0) 39 (53.0)
 School Level (years) ≤ 4 years 106 (21.0) 56 (22.0) 32 (23.0) 10 (20.0) 8 (16.0)
5–8 years 304 (61.0) 154 (59.0) 86 (61.0) 30 (61.0) 34 (67.0)
≥ 8 years 90 (18.0) 49 (19.0) 23 (16.0) 9 (18.0) 9 (18.0)
 Metropolitan Area Vitória 583 (61.0) 293 (59.0) 162 (61.0) 63 (72.0) 65 (60.0)
Vila Velha 89 (9.0) 49 (10.0) 25 (9.0) 7 (8.0) 8 (7.0)
Cariacica 120 (13.0) 60 (12.0) 34 (13.0) 9 (10.0) 17 (16.0)
Serra 123 (13.0) 70 (14.0) 36 (14.0) 4 (5.0) 13 (12.0)
Others 44 (5.0) 26 (5.0) 9 (3.0) 4 (5.0) 5 (5.0)
Clinical
 X Ray No 46 (6.0) 20 (5.0) 17 (9.0) 3 (4.0) 6 (7.0)
Yes 667 (94.0) 349 (95.0) 178 (91.0) 65 (96.0) 75 (93.0)
 TB Presentation PTBc 779 (81.0) 389 (78.0) 217 (82.0) 79 (91.0) 94 (87.0)
EPTB 111 (12.0) 71 (14.0) 26 (10.0) 6 (7.0) 8 (7.0)
PTB + EPTB 69 (7.0) 38 (8.0) 23 (9.0) 2 (2.0) 6 (6.0)
 AFB Smears Results Negative 147 (15.0) 82 (17.0) 48 (18.0) 6 (7.0) 11 (10.0)
Positived 802 (85.0) 413 (83.0) 214 (82.0) 81 (93.0) 94 (90.0)
Molecular
 Spoligotyping Non LAM 412 (48.0) 217 (46.0) 144 (61.0) 33 (47.0) 18 (22.0)
LAM 448 (52.0) 255 (54.0) 91 (39.0) 37 (53.0) 65 (78.0)
 RDRio Genotype Non RDRio 552 (60.0) 299 (62.0) 182 (70.0) 36 (50.0) 35 (33.0)
RDRio 369 (40.0) 184 (38.0) 78 (30.0) 36 (50.0) 71 (77.0)
  1. a – When the unique patterns (PU) were the reference group and were compared with all others genotyped TB cases by
  2. cluster size in number of patients per cluster
  3. b – Based on the SINAN response field for skin colour
  4. c– PTB = pulmonary TB, EPTB = extrapulmonary TB
  5. d- All smear positive results were stratified as + 1 (10–99 AFB/100 fields), + 2 (1–10 AFB/field) and + 3 (> AFB/field)
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