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Table 3 Characteristics of patients with and without acute biliary events

From: Acute biliary events during anti-tuberculosis treatment: hospital case series and a nationwide cohort study

 

ABE group (n = 195)

Non-ABE group (n = 159,371)

Age (years)a*

66.2 ± 13.5

56.6 ± 19.7

Maleb

132 (67.7)

109,399 (68.6)

Tuberculosis diagnostic yearb

 1996–2000

60 (30.8)

48,844 (30.6)

 2001–2005

73 (37.4)

59,424 (37.3)

 2006–2010

62 (31.8)

51,103 (32.1)

Co-morbidity (%)

 Diabetes mellitusb*

63 (37.4)

38,075 (23.9)

 Chronic obstructive pulmonary diseaseb

10 (5.1)

7918 (5.0)

 Malignancyb

12 (6.2)

6712 (4.2)

 End-stage renal diseasec

2 (1.0)

1998 (1.3)

 Connective tissue diseasec

0 (0.0)

1151 (0.7)

 Acquired immunodeficiency syndromec

1 (0.5)

562 (0.4)

 Liver cirrhosisc

1 (0.5)

323 (0.2)

 Transplantationc*

1 (0.5)

137 (0.1)

 Pneumoconiosisc

0 (0)

85 (0.1)

Low incomeb

5 (2.6)

4830 (3.0)

Total duration of anti-TB treatment

266.9 ± 99.7

260.4 ± 105.8

 Intensive phase (initial 60 days)a

  No. of days covered by isoniazida

47.7 ± 18.6

50.0 ± 11.2

  No. of days covered by rifamycina*

48.9 ± 13.4

51.7 ± 11.2

  No. of days covered by ethambutola

51.2 ± 11.4

50.8 ± 13.1

  No. of days covered by pyrazinamidea

39.9 ± 21.3

42.5 ± 20.4

 Initial 180 days

  No. of days covered by isoniazida*

134.4 ± 52.2

142.4 ± 53.4

  No. of days covered by rifamycina*

140.1 ± 37.9

152.5 ± 32.8

  No. of days covered by ethambutola

145.2 ± 35.6

141.9 ± 42.2

  No. of days covered by pyrazinamidea

67.8 ± 44.9

69.3 ± 45.8

  1. Data are presented as number (%) or mean ± standard deviation
  2. aCompared using an independent-sample t test
  3. bCompared using a chi-square test
  4. cCompared using a Fisher exact test
  5. *p < 0.05 for the comparison between the ABE and non-ABE groups