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Fig. 1 | BMC Infectious Diseases

Fig. 1

From: Persistent mammalian orthoreovirus, coxsackievirus and adenovirus co-infection in a child with a primary immunodeficiency detected by metagenomic sequencing: a case report

Fig. 1

Mammalian orthoreovirus infection confirmed by phylogenetic analysis and immunofluorescence staining. a Phylogenetic analysis of Mammalian orthoreovirus segment S1 isolated in this study (circle, mew716_S1_type_3_human) reveals a close relationship with previously described isolates identified in a child in Slovenia (triangle, KF154730), bats in Germany (JQ412761), and pigs in Italy (KX343206). Phylogenetic trees were constructed in MEGA7 using the Maximum Likelihood method based on the Kimura 2-parameter model. Bootstrap values from 1000 tries are shown. MRV-type and host species are depicted if available. b Anti-MRV-3 immunofluorescence of patient plasma before and after seroconversion on MRV-3-infected and uninfected Caco-2 cells

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BMC Infectious Diseases

ISSN: 1471-2334

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