| |
Non- SS
|
SS
| |
|---|
| |
(n = 98,310)
|
(n = 6554)
|
P-value
|
|---|
|
Age, years (mean ± SD)
|
54 ± 14
|
54 ± 14
|
1
|
|
< 50 years
|
34,140 (34.7)
|
2276 (34.7)
| |
|
≥ 50 years
|
64,170 (65.3)
|
4278 (65.3)
| |
|
Gender
| | |
1
|
|
Female
|
86,760 (88.3)
|
5784 (88.3)
| |
|
Male
|
11,550 (11.8)
|
770 (11.8)
| |
|
CCI (mean ± SD)
|
0.4 ± 1.0
|
0.5 ± 0.9
|
<0.001
|
|
CCI group
| | | |
|
0
|
76,836 (78.2)
|
4541 (69.3)
| |
|
≥ 1
|
21,474 (21.8)
|
2013 (30.7)
| |
|
Medications during all follow-up period
| | | |
|
Immunosuppressants
|
837(0.9)
|
1349(20.6)
|
<0.001
|
|
Methotrexate
|
391(0.4)
|
563(8.6)
|
<0.001
|
|
Azathioprine
|
84(0.1)
|
819(12.5)
|
<0.001
|
|
Cyclophosphamide
|
425(0.4)
|
208(3.2)
|
<0.001
|
|
Steroid
|
38,348(39.0)
|
4559(69.6)
|
<0.001
|
|
Medications during the first year
| | | |
|
Immunosuppressants
|
413 (0.4)
|
955 (14.6)
|
<0.001
|
|
Methotrexate
|
214 (0.2)
|
360 (5.5)
|
<0.001
|
|
Azathioprine
|
41 (0.0)
|
572 (8.7)
|
<0.001
|
|
Cyclophosphamide
|
178 (0.2)
|
150 (2.3)
|
<0.001
|
|
Steroid
|
19,828 (20.2)
|
3588 (54.8)
|
<0.001
|
-
Abbreviations: SS Sjögren’s Syndrome
