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Table 3 Social demographic differences between the mean community viral load and undetectable viral loads rates pre- and post-implementation of a “Treatment as Prevention” strategy for HIV-infected men who have sex with men in Hangzhou

From: Reduction in HIV community viral loads following the implementation of a “Treatment as Prevention” strategy over 2 years at a population-level among men who have sex with men in Hangzhou, China

Variables

Pre-implementation

Post-implementation

Kruskal-Wallisa

VL≤400%a

mCVL

VL median(IQR)

Kruskal-Wallis

VL≤400%

P-value

mCVL

VL median(IQR)

Kruskal-Wallis

VL≤400%

P-value

Overall

579

18,451(3110–83,502)

 

50.0

 

33

10(10–10)

 

84.7

 

<0.001

<0.001

Marital status

  

<0.001

 

<0.001

  

0.024

 

0.007

  

 Single

1058

3000(10–41,002)

 

38.1

 

34

10(10–23)

 

81.3

 

<0.001

<0.001

 Married/cohabitation

78

10(10–259)

 

77.8

 

17

10(10–10)

 

91.7

 

<0.001

0.027

 Divorced/separated

150

25(10–4893)

 

63.7

 

12

10(10–10)

 

94.2

 

<0.001

<0.001

Ethnicity

  

0.071

 

0.093

  

0.201

 

0.225

  

 Han

434

350(10–19,002)

 

50.5

 

27

10(10–10)

 

84.4

 

<0.001

<0.001

 Minority

6265

35,003(2105–75,499)

 

22.2

 

10

10(10–10)

 

100.0

 

0.003

0.001

Education

  

0.016

 

0.013

  

0.012

 

0.138

  

 Junior high school and below

234

55(10–9900)

 

59.0

 

17

10(10–10)

 

88.6

 

<0.001

<0.001

 High school and junior college

475

620(10–29,677)

 

48.6

 

17

10(10–10)

 

87.7

 

<0.001

<0.001

 College

795

1900(10–41,350)

 

43.2

 

38

10(10–108)

 

81.4

 

<0.001

<0.001

Age, years

  

<0.001

 

<0.001

  

0.135

 

0.031

  

 < 25

1049

2790(10–40,004)

 

34.4

 

41

10(10–195)

 

77.9

 

<0.001

<0.001

 25–29

947

3100(10–33,027)

 

40.5

 

25

10(10–10)

 

85.5

 

<0.001

<0.001

 30–39

360

160(10–22,849)

 

55.3

 

22

10(10–10)

 

86.6

 

<0.001

<0.001

 ≥ 40

84

10(10–10)

 

77.2

 

17

10(10–10)

 

93.0

 

<0.001

0.006

CD4 count (cells/μL)

  

0.943

 

0.215

  

0.034

 

0.349

  

 0–199

492

230(10–31,501)

 

54.7

 

99

10(10–1567)

 

75.0

 

0.043

0.074

 200–349

515

140(10–28,051)

 

55.0

 

40

10(10–60)

 

83.3

 

<0.001

<0.001

 350–499

509

350(10–15,999)

 

43.4

 

25

10(10–10)

 

86.5

 

<0.001

<0.001

 ≥ 500

739

1800(10–20,749)

 

50.1

 

28

10(10–10)

 

85.2

 

<0.001

<0.001

Received ART

  

<0.001

 

<0.001

  

<0.001

 

<0.001

  

 No

11,241

18,451(3110–83,502)

 

10.8

 

3476

4109(1165–19,902)

15.1

 

<0.001

0.326

 Yes

32

10(10–43)

 

87.6

 

12

10(10–10)

 

98.1

 

<0.001

<0.001

Registered residence

  

0.055

 

0.041

  

0.022

 

0.164

  

 Local

408

206(10–19,999)

 

52.1

 

10

10(10–10)

 

83.5

 

<0.001

<0.001

 Nonlocal

902

1900(25–24,998)

 

39.8

 

14

10(10–10)

 

84.7

 

<0.001

<0.001

  1. a Pre- versus post-implementation
  2. Acronyms: mCVL mean community viral load, VL viral load, χ2 chi squared test, AOR adjusted odds ratio, CI confidence interval, ART, antiretroviral therapy