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Table 1 Characteristics of the population

From: Adipokines levels in HIV infected patients: lipocalin-2 and fatty acid binding protein-4 as possible markers of HIV and antiretroviral therapy-related adipose tissue inflammation

Characteristics

HIVneg CTR (10)

HIV (40)

P value

Female (%)

5 (50%)

14 (35%)

0.4

Age (years)

45.3 ± 11.7

44.1 ± 8.2

0.8

Years since HIV diagnosis

n/a

3.5 (1.0–9.5)

HIV RNA > = 50 copies

n/a

13 (33%)

CD4 (cell/mm3)

n/a

608 (447–849)

BMI (kg/m2)

23.4 ± 2.9

24.4 ± 3.0

0.36

Waist circumference (cm)

85 ± 10

87 ± 9

0.99

Fat Mass (% of total mass)

21.8 ± 10.3

23.3 ± 8.6

0.25

Systolic Blood pressure (mmHg)

113 ± 8

119 ± 12

0.29

Diastolic Blood pressure (mmHg)

76 ± 5

80 ± 9

0.32

Hypertension

1 (10%)

16 (40%)

0.13

Fasting Blood Glucose (mg/dl)

87.3 ± 11.4

103.8 ± 19.8

0.02

Fasting Insulin (U/L)

6.6 (5.4–8.7)

6.0 (3.3–9.8)

0.70

HOMA-IR

1.5 (1.1–1.8)

1.5 (0.8–2.5)

0.83

Hyperglycemia

1 (10%)

21 (53%)

0.03

Tot-Cholesterol (mg/dl)

188 ± 35

217 ± 52

0.06

Triglycerides (mg/dl)

73 ± 20

176 ± 160

0.06

HDL-chol (mg/dl)

56 ± 14

48 ± 20

0.41

LDL-chol (mg/dl)

117 ± 28

133 ± 37

0.13

Non HDL-chol (mg/dl)

132 ± 31

168 ± 55

0.04

Metabolic Syndrome n (%)

0 (0%)

14 (35%)

0.03

HALS n (%)

12 (30%)

10 years CVD risk score (%)

1.5 (0.8–6.5)

8.0 (2.5–18.6)

0.01

hsCRP (mg/L)

1.1 (0.8–1.6)

2.0 (2.9–3.7)

0.001

Lipocalin-2 (ng/ml)

31.0 ± 7.9

47.3 ± 17.7

0.007

FABP4 (ng/ml)

13.1 ± 4.1

15.6 ± 7.6

0.12

  1. Legend: BMI Body Mass Index, HOMA-IR homeostasis model assessment of insulin resistance, HALS HIV/ART Associated Lipodystrophy Syndrome, CVD Cardiovascular Diseases, FABP4 Fatty Acid Binding Protein 4