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Table 3 In vitro susceptibilities of 157 clinical isolates to four antifungal agents. MIC range, geometric mean, MIC50, and MIC90 values are expressed in μg/ml

From: Identification of uncommon oral yeasts from cancer patients by MALDI-TOF mass spectrometry

(No. of strains) Antifungal agent MIC μg/ml
MIC range MIC50 MIC90 GM MODE
All clinical strains (n = 157) Fluconazole 0.063–64 2 8 1.65 4
Amphotericin B 0.016–16 1 4 0.50 1
Caspofungin 0.008–8 0.5 mg/ml 2 μg/ml 0.34 0.5
Anidulafungin 0.008–1 0.063 0.5 0.06 0.063
C. albicans (n = 82) Fluconazole 0.063–64 0.5 8 0.80 0.5
Amphotericin B 0.016–16 1 4 0.62 1
Caspofungin 0.008–8 0.25 1 0.22 0.5
Anidulafungin 0.008–0.25 0.031 0.125 0.03 0.016
C. dubliniensis (n = 6) Fluconazole 0.063–0.125 0.125 0.125 0.11 0.125
Amphotericin B 0.016–2 0.031 2 0.09 0.031
Caspofungin 0.25–2 0.5 2 0.5 0.5
Anidulafungin 0.008–0.125 0.125 0.25 0.07 0.016
C. glabrata (n = 40) Fluconazole 0.25–64 8 64 7.08 4
Amphotericin B 0.016–4 1 2 0.62 1
Caspofungin 0.008–2 0.5 2 0.40 1
Anidulafungin 0.016–1 0.063 1 0.12 1
C. krusei (= Pichia kudriavzevii) (n = 16) Fluconazole 0.25–64 8 64 7.33 4
Amphotericin B 0.063–2 0.5 1 0.59 1
Caspofungin 0.063–4 2 4 1.13 1
Anidulafungin 0.016–0.25 0.125 0.25 0.07 0.25
C. tropicalis (n = 7) Fluconazole 0.063–8 4 8 0.63 0.063
Amphotericin B 0.031–2 1 2 0.39 2
Caspofungin 0.031–8 0.5 8 0.39 0.25
Anidulafungin 0.008–0.063 0.063 0.063 0.063 0.063
C. kefyr = (Kluyveromyces marxianus) (n = 6) Fluconazole 0.25–32 4 32 2.82 4
Amphotericin B 0.016–1 0.5 1 0.15 0.5
Caspofungin 0.125–0.05 0.25 0.5 0.25 0.125
Anidulafungin 0.031–0.063 0.063 0.5 0.04 0.063