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Table 2 Parameters on ECMO, IPPV parameters and physiological indicators pre and on ECMO

From: Application of extracorporeal membrane oxygenation in patients with severe acute respiratory distress syndrome induced by avian influenza A (H7N9) viral pneumonia: national data from the Chinese multicentre collaboration

Variable

6 h pre-ECMO

24 h on ECMO

48 h on ECMO

72 h on ECMO

P value

Blood flow (L/min)

–

3.84 ± 0.87

4.48 ± 0.77

4.18 ± 1.00

0.023*

IPPV parameters

 FiO2

94 (55–100)

50 (40–80)

45 (40–60)

46 (40–50)

<0.001*

 PEEP (cmH2O)

14 ± 4

12 ± 5

11 ± 3

11 ± 2

0.022*

 VT (ml)

439 ± 61

285 ± 94

317 ± 103

308 ± 128

<0.001*

 Pplat (cmH2O)

29 ± 8

23 ± 6

23 ± 5

24 ± 7

0.004*

Physiological indicators

 Heart Rate (/min)

103 ± 27

90 ± 24

85 ± 22

90 ± 25

0.025*

 MAP (mmHg)

84 ± 15

87 ± 15

81 ± 21

94 ± 17

0.057

 Respiratory Rate (/min)

31 ± 7

19 ± 6

16 ± 6

16 ± 6

<0.001*

 pH

7.33 ± 0.10

7.42 ± 0.10

7.39 ± 0.10

7.43 ± 0.10

0.006*

 PaCO2 (mmHg)

52.4 ± 16.6

34.1 ± 9.8

38.3 ± 10.5

38.2 ± 7.8

<0.001*

 PaO2 (mmHg)

56.3 ± 20.9

90.0 ± 35.9

94.8 ± 45.7

104.4 ± 57.5

<0.001*

 Lactate (mmol/L)

2.8 ± 1.9

3.1 ± 3.7

4.0 ± 4.8

2.9 ± 2.7

0.625

  1. Note: ECMO extracorporeal membrane oxygenation, IPPV invasive positive pressure ventilation, FiO 2 fraction of inspiration, PEEP positive end-expiratory pressure, VT tidal volume, P plat plateau pressure, MAP mean arterial pressure, SpO 2 fingertip pulse oxygen saturation, PaCO 2 partial pressure of arterial carbon dioxide, PaO 2 partial pressure of arterial oxygen
  2. *P < 0.05