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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: Application of extracorporeal membrane oxygenation in patients with severe acute respiratory distress syndrome induced by avian influenza A (H7N9) viral pneumonia: national data from the Chinese multicentre collaboration

Fig. 2

Comparison of IPPV parameters and ABGs between two groups of patients on ECMO. For the successfully weaned group compared to the unsuccessfully weaned group, FiO2 was 46 ± 13% vs. 74 ± 25%, respectively, at 48 h (P < 0.01) and 45 ± 11% vs. 78 ± 24%, respectively, at 72 h (P < 0.01). The monitored Pplat was 21 ± 3 cmH2O vs. 25 ± 5 cmH2O, respectively, at 48 h (P < 0.05) and 19 ± 4 cmH2O vs. 29 ± 6 cmH2O, respectively, at 72 h (P < 0.01). The monitored VT was 246 ± 93 ml vs. 343 ± 96 ml, respectively, at 48 h (P < 0.05) and 236 ± 113 ml vs. 356 ± 116 ml, respectively, at 72 h (P < 0.05) after ECMO support. However, there were no differences in PEEP during ECMO between the two groups. Patients who were in the unsuccessfully weaned group compared to patients in the successfully weaned group had severe acidosis (pH: 7.29 ± 0.14 vs. 7.40 ± 0.05, respectively, (P < 0.01), a higher PaCO2 (57.0 ± 16.7 mmHg vs. 43.6 ± 13.0 mmHg, respectively, (P < 0.05), and a higher lactate concentration (3.6 ± 2.1 mmol/L vs. 1.7 ± 0.8 mmol/L, respectively (P < 0.05), pre-ECMO. The pH and PaCO2 did not significantly differ between the two groups during ECMO therapy, while patients who eventually weaned successfully from ECMO had a gradual ascending tendency in PaO2 at 48 and 72 h on ECMO and a sustained low level of lactate after ECMO therapy

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