| |
Sporadic n = 32
|
Familial n = 41
|
P value
|
|---|
|
Age at diagnosis, years
|
2.1 (0.8–34.2)
|
1.0 (0.6–3.0)
|
0.04
|
|
Male sex
|
11a (44)
|
25(61)
|
0.18
|
|
Clinical events
|
|
Sepsis and/ or meningitis
|
25(78)
|
24 (58)
|
0.08
|
|
Others
|
6 (19)
|
2 (5)
|
0.06
|
|
Asymptomatic
|
1 (3)
|
15 (37)
|
0.001
|
|
Pathogens
|
|
S. pneumoniae
|
16b (62)
|
14c (56)
|
0.69
|
|
H. influenzae
|
5b (19)
|
3c (12)
|
0.48
|
|
Others
|
3b (12)
|
0c (0)
|
0.08
|
|
Howell- Jolly bodies
|
18 (56)
|
17 (41)
|
0.21
|
|
Outcome
|
|
Death
|
12 (38)
|
16 (39)
|
0.68
|
- Values are presented as median (interquartile range) or number (percentage). P < 0.05 is considered to be significant. adata from 25 patients were available. bdata from 26 patients were available. cdata from 25 patients were available
