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Table 1 Reported cases of sporadic congenital isolated asplenia

From: Sporadic isolated congenital asplenia with fulminant pneumococcal meningitis: a case report and updated literature review

Case no. Age at diagnosis Sex Clinical events Pathogens Howell-Jolly bodies Outcome Reference
1 2 months Female Meningitis H. influenzae Yes Survived [13]
2 4 months Unknown Sepsis E. coli NA Died [11]
3 6 months Unknown Sepsis S. Pneumoniae NA Survived [11]
4 6 months Female Sepsis, purpura fulminans Unknown Yes Survived [3]
5 7 months Male Sepsis, bilateral adrenal hemorrhage H. influenzae NA Died in 12 h [15]
6 7 months Female Asymptomatic No infection Yes Alive [3]
7 10 months Unknown Sepsis H. influenzae NA Survived [11]
8 10 months Male Sepsis, purpura fulminans S. pneumoniae Yes Died in 20 h [3]
9 11 months Female Meningitis, purpura fulminans S. pneumoniae Yes Survived Present case
10 12 months Female Sepsis, purpura fulminans S. pneumoniae Yes Survived [3]
11 12 months Male Meningitis (twice), osteomyelitis S. pneumoniae Yes Survived [14]
12 20 months Female Sepsis Unknown Yes Survived [3]
13 21 months Unknown Sepsis S. pneumoniae NA Survived [11]
15 1 years Unknown Sepsis S. pneumoniae NA Survived [27]
16 2 years Male Sepsis, bilateral adrenal hemorrhage H. influenzae NA Died in 32 h [15]
17 2 years Female Meningitis (3 times) E. coli, S. pneumoniae Yes Survived [5]
     H. influenzae    
18 3 years Unknown Sepsis H. influenzae NA Died in 24 h [11]
19 4 years Female Sepsis, bilateral adrenal hemorrhage S. pneumoniae NA Died in 12 h [18]
20 5 years Male Sepsis, meningitis S. pneumoniae NA Died [23]
21 10 years Female Sepsis, arthritis (twice) S. pneumoniae NA Died in 24 h [21]
22 15 years Male Meningitis (twice), bilateral adrenal hemorrhage S. pneumoniae Yes Died in 3 h [12]
23 28 years Male Sepsis Group B streptococcus Yes Survived [24]
24 20 years Male Tonsillitis Unknown Yes Alive [22]
25 36 years Male Meningitis, bilateral adrenal hemorrhage S. pneumoniae NA Died in 29 h [10]
26 37 years Female Thrombocytosis No infection Yes Alive [16]
27 44 years Female Thrombocytosis No infection Yes Alive [25]
28 56 years Female Thrombocytosis No infection Yes Alive [20]
29 56 years Male Thrombocytosis No infection Yes Alive [20]
30 60 years Female Meningitis S. pneumoniae Yes Survived [19]
31 67 years Female Sepsis S. pneumoniae NA Died in 24 h [26]
32 72 years Male Thrombocytosis No infection Yes Alive [28]
  1. NA Not available