Sporadic isolated congenital asplenia with fulminant pneumococcal meningitis: a case report and updated literature review

Iijima, Shigeo

doi:10.1186/s12879-017-2896-5

Table 1 Reported cases of sporadic congenital isolated asplenia

From: Sporadic isolated congenital asplenia with fulminant pneumococcal meningitis: a case report and updated literature review

Case no.	Age at diagnosis	Sex	Clinical events	Pathogens	Howell-Jolly bodies	Outcome	Reference
1	2 months	Female	Meningitis	H. influenzae	Yes	Survived	[13]
2	4 months	Unknown	Sepsis	E. coli	NA	Died	[11]
3	6 months	Unknown	Sepsis	S. Pneumoniae	NA	Survived	[11]
4	6 months	Female	Sepsis, purpura fulminans	Unknown	Yes	Survived	[3]
5	7 months	Male	Sepsis, bilateral adrenal hemorrhage	H. influenzae	NA	Died in 12 h	[15]
6	7 months	Female	Asymptomatic	No infection	Yes	Alive	[3]
7	10 months	Unknown	Sepsis	H. influenzae	NA	Survived	[11]
8	10 months	Male	Sepsis, purpura fulminans	S. pneumoniae	Yes	Died in 20 h	[3]
9	11 months	Female	Meningitis, purpura fulminans	S. pneumoniae	Yes	Survived	Present case
10	12 months	Female	Sepsis, purpura fulminans	S. pneumoniae	Yes	Survived	[3]
11	12 months	Male	Meningitis (twice), osteomyelitis	S. pneumoniae	Yes	Survived	[14]
12	20 months	Female	Sepsis	Unknown	Yes	Survived	[3]
13	21 months	Unknown	Sepsis	S. pneumoniae	NA	Survived	[11]
15	1 years	Unknown	Sepsis	S. pneumoniae	NA	Survived	[27]
16	2 years	Male	Sepsis, bilateral adrenal hemorrhage	H. influenzae	NA	Died in 32 h	[15]
17	2 years	Female	Meningitis (3 times)	E. coli, S. pneumoniae	Yes	Survived	[5]
				H. influenzae
18	3 years	Unknown	Sepsis	H. influenzae	NA	Died in 24 h	[11]
19	4 years	Female	Sepsis, bilateral adrenal hemorrhage	S. pneumoniae	NA	Died in 12 h	[18]
20	5 years	Male	Sepsis, meningitis	S. pneumoniae	NA	Died	[23]
21	10 years	Female	Sepsis, arthritis (twice)	S. pneumoniae	NA	Died in 24 h	[21]
22	15 years	Male	Meningitis (twice), bilateral adrenal hemorrhage	S. pneumoniae	Yes	Died in 3 h	[12]
23	28 years	Male	Sepsis	Group B streptococcus	Yes	Survived	[24]
24	20 years	Male	Tonsillitis	Unknown	Yes	Alive	[22]
25	36 years	Male	Meningitis, bilateral adrenal hemorrhage	S. pneumoniae	NA	Died in 29 h	[10]
26	37 years	Female	Thrombocytosis	No infection	Yes	Alive	[16]
27	44 years	Female	Thrombocytosis	No infection	Yes	Alive	[25]
28	56 years	Female	Thrombocytosis	No infection	Yes	Alive	[20]
29	56 years	Male	Thrombocytosis	No infection	Yes	Alive	[20]
30	60 years	Female	Meningitis	S. pneumoniae	Yes	Survived	[19]
31	67 years	Female	Sepsis	S. pneumoniae	NA	Died in 24 h	[26]
32	72 years	Male	Thrombocytosis	No infection	Yes	Alive	[28]

NA Not available

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ISSN: 1471-2334

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