Fig. 1

Candida tropicalis clinically isolated from the oral mucosa of a patient with laryngeal carcinoma prior to any cancer or antifungal treatment. The top line shows images of non-irradiated yeast (NI) and the lower line shows images of yeast after receiving a cumulative dose of 7200 cGy (i). Parental phenotypes of colonies of NI yeast with ring morphology (a, b) and parental phenotypes of I yeast with smooth morphology (f, g). Scanning electron microscopy showing the microstructure of colonies after 96 h of cultivation in YPD agar at 25 °C: surface of parental colony of NI yeasts with ring morphology (c) and surface of parental colony of I yeasts with smooth morphology (h). Ultrastructure of parental colony of NI yeasts, ring morphology, where blastoconidia and pseudohyphae are observed (d, e) and parental colony of I yeasts, smooth morphology, absence of pseudohyphae and thick extracellular matrix indicated by white arrows (i, j)