Factors contributing to anaemia after uncomplicated falciparum malaria in under five year-old Nigerian children ten years following adoption of artemisinin-based combination therapies as first-line antimalarials

Table 2 Predictors of anaemia at presentation in children <5 years with uncomplicated falciparum malaria

Variable	Total no.	No. with anaemia at presentation	OR (95% CI)	P value	AOR (95% CI)	P value
Gender
Female	437	158	1
Male	522	197	1.1 (0.8–1.4)	0.66	–	–
Age (months)
> 15	837	296	1		1
≤ 15	114	56	1.8 (1.2–2.6)	0.01	1.5 (0.9–2.5)	0.09
Duration of illness (days)
≤ 2	295	92	1		1
> 2	330	138	1.6 (1.1–2.2)	0.01	1.5 (1.1–2.1)	0.02
Enrolment body temperature (°C)
≤ 37.4	357	143	1
> 37.4	601	211	0.8 (0.6–1.1)	0.14	–	–
History of fever
Absent	169	70	1
Present	789	284	1.2 (0.9–1.8)	0.22	–	–
Asexual parasitaemia (μL⁻¹)
> 10,000	389	160	1		1
≤ 10,000	564	193	1.3 (1.1–1.8)	0.003	1.5 (1.1–2.2)	0.02
Gametocyte carriage at presentation
Absent	912	333	1
Present	47	22	1.5 (0.6–2.8)	0.2	–	–
Season of enrolment
Dry (November–March)	69	24	1
Wet (April–October)	890	331	1.1 (0.7–1.9)	0.79	–	–
Region of enrolment
Eastern flank^a	456	180	1
Western flank^b	503	175	0.8 (0.6–1.1)	0.15	–	–

OR odd ratio, AOR adjusted odd ratio, CI confidence interval
^aEastern flank includes: Numan, Neni, Ogbia and Ogwa in Adamawa, Anambra, Bayelsa and Imo States, respectively
^bWestern flank includes: Kura, Ilorin, Ibadan and Bodinga in Kano, Kwara, Oyo and Sokoto States, respectively

ISSN: 1471-2334