Decision tree for accurate infection timing in individuals newly diagnosed with HIV-1 infection

BMC Infectious Diseases

Table 4 Result of infection timing for cross-sectional samples from 566 newly diagnosed individuals

INNO-LIA	p31	LAg-Avidity EIA	BED CEIA			Decision tree
INNO-LIA	p31	LAg-Avidity EIA	BED CEIA	n		Seroconversion	Very early	Early	Recent	Long term	Advanced
Negative/ID	Recent	Recent	Recent	24	Congruent	24
Positive	Recent	Recent	Recent	81			81
Positive	Long-term	Recent	Recent	56				56
Positive	Long-term	Long-term	Recent	74					71		3
Positive	Long-term	Long-term	Long-term	313						313
Positive	Recent	Long-term	Recent	8	Incongruent						8
Positive	Long-term	Recent	Long-term	1						1
Positive	Recent	Long-term	Long-term	9						9
				566

Results that are in-line with the expectations when considering the differences in recency window are labeled as ‘congruent’ and results that are not in-line with these expectations are labeled as ‘incongruent’
Abbreviations: ID indeterminate, EIA Enzyme Immuno Assay, CEIA Capture Enzyme Immuno Assay, INNO-LIA Innogenetics Line Immuno Assay

ISSN: 1471-2334