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Table 1 List of parameters and other notation

From: A comparison of the test-negative and the traditional case-control study designs for estimation of influenza vaccine effectiveness under nonrandom vaccination

Symbol

Definition

Values

X

Health status

0 - frail

  

1 - healthy

V

Vaccination status

0 - unvaccinated

  

1 - vaccinated

Y

ARI and influenza infection status

0 - no ARI

  

1 - NFARI

  

2 - FARI

M

Seeking medical care for ARI

0 - no

  

1 - yes

T

Result of test for influenza infection

0 - negative

  

1 - positive

C A

Case/control status in TND study

0 - control

  

1 - case

C B

Case/control status in TCC study

0 - control

  

1 - case

B

Participating in TCC study

0 - no

  

1 - yes

Ď€

Probability of having better health status (i.e. healthy persons)

0.7

α x

Probability of being vaccinated for a person of health status x

 

β vx

Probability of NFARI for a person of vaccination status v and health status x

 

\(\rho _{\beta } = {{\beta _{1x}}\over {\beta _{0x}}}\)

Ratio comparing vaccinees and non-vaccinees w.r.t. probability of NFARI

0.5-2.0

\(\eta _{\beta } = {{\beta _{v1}}\over {\beta _{vo}}}\)

Ratio comparing healthy and frail persons w.r.t. probability of NFARI

0.5-1.0

Îł vx

Probability of FARI for a person of vaccination status v and health status x

 

\(\rho _{\gamma } = {{\gamma _{1x}}\over {\gamma _{0x}}}\)

Ratio comparing vaccinees and non-vaccinees w.r.t. probability of FARI

0.4a

\(\eta _{\gamma } = {{\gamma _{v1}}\over {\gamma _{v0}}}\)

Ratio comparing healthy and frail persons w.r.t. probability of FARI

0.5-1.0

δ SN

Probability of seeking medical care for ARI for an unvaccinated frail person with NFARI

 

δ SF

Probability of seeking medical care for ARI for an unvaccinated frail person with FARI

 

λ

multiplier for the probability of seeking medical care for FARI or NFARI for a healthy person

0.5-2.0

Ψ F

multiplier for the probability of seeking medical care for FARI for a vaccinated person

0.5-1.0

Ď„ e

Probability that a person of illness/infection status e tests positive for influenza infection

Ď„ 1=0, Ď„ 2=1

  1. aAssumes a true VE of 60%. Thus, the probability of FARI in a vaccinee is 40% that of a non-vaccinee