Acquisition and persistence of strain-specific methicillin-resistant Staphylococcus aureus and their determinants in community nursing homes

Table 2 Coefficients of ENET models for strains discriminated at the 95% strain similarity threshold

Covariates (strain-specific events)	Estimated coefficients associated with the outcome variables (candidate risk factors)
Covariates (strain-specific events)	AB	Hosp	Dev	Wnd	Comorb	Func	Cogn
(Intercept)	−0.56	−1.69	−2.25	−2.30	−0.39	0.75	−1.39
C0100	0.68	0.38	0.69	–	0.50	0.69	–
T0100	–	−1.65	–	NA	–	–	1.10
C0101	1.17	–	–	–	–	–	–
C0104	NA	–	–	–	−1.75	–	–
C0106	–	–	–	–	−0.68	1.12	–
T0106	0.99	1.45	–	3.34	–	–	–
C0113	–	–	0.06	1.43	–	3.47	−4.40
T0113	NA	–	–	1.25	–	–	–
C0114	0.96	NA	–	–	–	–	–
C0118	–	–	0.61	–	1.65	–	–
C0119	–	–	1.94	–	2.71	3.08	–
T0119	–	–	–	–	2.55	–	–
C0120	–	−1.56	–	–	–	–	–
T0124	–	–	–	0.17	–	–	–
C0139	–	–	–	–	1.09	–	–
C0146	–	–	–	1.49	–	−1.13	–
C0149	–	–	2.05	–	1.48	–	–
C0154	−0.54	–	–	–	2.91	−2.29	–
T0157	–	–	NA	–	–	–	–
C0300	0.55	–	1.19	0.52	0.78	3.70	0.97
T0300	0.54	–	–	–	–	–	–
C0301	–	–	1.20	1.95	–	3.15	1.53
T0301	–	–	–	–	–	2.99	–
C1201	−1.28	–	–	–	2.85	2.99	6.96
Facility ^a	0.09	NA	NA	NA	0.13	0.03	−0.15

In these models, candidate risk factors served as dependent variables, while strain-specific acquisition and carriage events and Facility were included as independent variables. The rows represent the acquisition and carriage events which were a part of the Markov blanket of at least one potential risk factor. The columns display the estimates of the covariates selected by the models from the Markov blankets of the respective potential risk factors. NA’s denote the strain-specific events included in the Markov blanket of a risk factor but not selected by the model, while dashes signify the events that were not in the Markov blankets of the respective risk factors (e.g., C0104 was in the Markov blanket of AB, but was not selected by the model; T0100 was not in the Markov blanket of AB)
^aFacility was included into the models as explanatory variable in addition to Markov blankets of the outcomes
T and C followed by a 4-digit sequence indicate acquisition and carriage events for the associated strain, respectively
AB, antibiotic use in the past 3 months (0 = Non-exposed, 1 = Exposed); Hosp, hospitalizations in the past 3 months (0 = Non-exposed, 1 = Exposed); Dev, presence of invasive device (0 = Non-exposed, 1 = Exposed); Wnd, presence of wound (0 = Non-exposed, 1 = Exposed); Comorb, comorbidity (0 = Non-severe, 1 = Severe); Func, functional status (0 = Non-severe, 1 = Severe); Cogn, cognitive status (0 = Non-severe, 1 = Severe)

ISSN: 1471-2334