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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: Effects of IFN-γ coding plasmid supplementation in the immune response and protection elicited by Trypanosoma cruzi attenuated parasites

Fig. 2

Control of parasite replication in animals primed with TCC+ pVXVR-mIFN-γ after lethal challenge. Thirty days after the last dose with attenuated parasites and plasmid DNA, animals were challenged with 500 blood trypomastigotes from the Tulahuen strain (n = 4). a Survival rate during the challenge period; b parasite load in peripheral blood as determined by fresh blood mount and (c) parasite load in heart as determined by Real Time PCR 30 days post challenge. Data are representative of three independent experiments. * p < 0.05 and ** p < 0.01 Kruskal-Wallis test for single-day measurements with Dunn’s Multiple Comparison Test

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