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Table 2 Non-susceptibility rates of different genotypes of SA in pediatric population in China

From: Multiresistant ST59-SCCmec IV-t437 clone with strong biofilm-forming capacity was identified predominantly in MRSA isolated from Chinese children

 

Isolates (n)

PEN

CXM

ERY

CLI

TET

GEN

CHL

RIF

CIP

SXT

LZD

VAN

MUP

TGC

FUS

MDRa

MRSA

60

96.7

38.4

100.0

83.3

40.0

5.0

63.3

3.3

20.0

0

0

0

0

0

1.7

76.7

 ST59-SCCmec IV-t437

37

97.3

45.9

100.0

91.9

54.1

2.7

70.3

2.7

18.9

0

0

0

0

0

0

83.8

 Others

23

95.7

26.1

100.0

69.6

82.6

8.7

52.2

4.3

21.7

0

0

0

0

0

4.3

65.2

MSSA

44

95.5

0

100.0

31.8

18.2

25.0

61.4

0

13.6

0

0

0

0

0

0

77.3

 ST5-t002

4

75.0

0

100.0

75.0

25.0

75.0

50.0

0

0

0

0

0

0

0

0

75.0

 ST6-t701

4

100.0

0

100.0

0

0

0

75.0

0

0

0

0

0

0

0

0

75.0

 ST22-t309

8

100.0

0

100.0

12.5

12.5

0

37.5

0

0

0

0

0

0

0

0

62.5

 ST188-t189

4

100.0

0

100.0

25.0

25

25.0

75.0

0

25.0

0

0

0

0

0

0

75.0

 Others

24

95.8

0

100.0

37.5

20.8

29.2

66.7

0

20.8

0

0

0

0

0

0

83.3

Total

104

96.2

22.1

100.0

61.5

30.8

13.4

62.5

1.9

17.3

0

0

0

0

0

0

85.6

P value

 

1.000

<0.0001

–

<0.0001

0.0193

0.0069

0.8408

0.5071

0.4431

–

–

–

–

–

1.000

1.000

  1. PEN Penicillin, CXM Cefuroxime, ERY Erythromycin, CLI Clindamycin, TET Tetracycline, GEN Gentamicin, CHL Chloramphenicol, CIP Ciprofloxacin, RIF Rifampin, SXT Trimethoprim-sulfamethoxazole, LNZ Linezolid, VAN Vancomycin, MUP Mupirocin, TGC Tigecycline, FA Fusidic acid
  2. a MDR multi-drug resistance. MDR-MRSA, resistant to ≥ 3 classes of non-β-lactam antimicrobials; MDR-MSSA, resistant to ≥ 3 classes of antibiotics including β-lactam antibiotics