Table 3 The resistance of antibiotic among all the S. pneumoniae
Antibiotic | No. of studies | Total no. of included strains | No. of included strains with antibiotic resistant | Resistant rate(%) (95%CI) | I 2 | P | P value of Egger’s test | P value of Egger’s test |
|---|---|---|---|---|---|---|---|---|
Penicillin | 20 | 2105 | 541 | 28.9(20.4, 37.4) | 69.9 | 0.000 | 0.147 | 0.298 |
Cefaclor | 6 | 499 | 463 | 65.8(51.2, 80.4) | 91.6 | 0.000 | 0.434 | 0.462 |
Ceftriaxone | 8 | 771 | 90 | 19.4(9.2, 29.5) | 96.9 | 0.000 | 0.175 | 0.266 |
Levofloxacin | 13 | 1175 | 159 | 2.5(0.3, 4.6) | 70.2 | 0.009 | 0.226 | 0.602 |
Erythromycin | 14 | 1635 | 1185 | 65.9(57.0, 74.9) | 93.6 | 0.000 | 0.131 | 0.108 |
Clindamycin | 9 | 878 | 675 | 64.0(45.5, 82.5) | 96.2 | 0.000 | 0.247 | 0.221 |
Tetracycline | 12 | 1334 | 967 | 67.1(33.8,96.4) | 99.7 | 0.000 | 0.249 | 0.548 |
Cotrimoxazole | 13 | 1524 | 1103 | 64.5(51.2, 77.8) | 96.7 | 0.000 | 1.000 | 0.704 |
Chloromycetin | 13 | 1524 | 360 | 24.1(16.7, 31.5) | 91.8 | 0.000 | 0.039 | 0.019 |