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Table 2 Seminal HPV prevalence by region, specimen type, and detection method

From: Human papillomavirus in semen and the risk for male infertility: a systematic review and meta-analysis

 

General Population

Fertility Clinic Attendees

No. of studies

No. of HPV positive

HPV DNA prevalence

(%) (95%CIa)

No. of studies

No. of HPV positive

HPV DNA prevalence

(%) (95%CIa)

Region

 Europe

10

149

15.2 (8.3-22.1)

10

285

17.9 (13.0-22.7)

 Asia

2

39

9.2 (0.3-18.0)

5

157

22.0 (11.4-32.5)

 North America

3

33

4.5 (2.9-6.0)

2

23

19.3 (0.0-49.8)

 Africa

0

–

–

1

18

28.6 (17.4-39.7)

 Ocean

0

–

–

1

5

29.4 (7.8-51.1)

 Latin America

0

–

–

1

29

38.2 (27.2-49.1)

Specimen type

 Non-centrifuged semen

9

133

12.4 (6.7-18.0)

7

205

20.8 (13.1-28.5)

 Centrifuged semen

6

88

10.9 (5.4-16.3)

11

278

18.0 (12.8-23.3)

 Unclear

0

–

–

2

34

36.4 (26.6-46.1)

Detection method

 Consensus primers

13

215

11.0 (7.3-14.7)

14

397

18.7 (14.2-23.1)

 Type-specific primers

2

6

19.0 (5.2-32.8)

5

78

27.4 (8.5-46.2)

 Others

0

–

–

1

42

18.6 (13.5-23.7)

  1. a Abbreviations: CI confidence interval