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Table 2 Comparison of characteristics of patients with spondylodiscitis caused by coagulase-negative staphylococcus (CoNS) and caused by Staphylococcus aureus

From: Characteristics of spontaneous coagulase-negative staphylococcal spondylodiscitis: a retrospective comparative study versus Staphylococcus aureus spondylodiscitis

 

1: S.aureus

n = 30

2: CoNS

total

n = 26

3: CoNS

confirmed

n = 15

4:CoNS

probable

n = 11

p

1 vs 2

p

1 vs 3

p

3 vs 4

Age (mean [95% CI])

61 [56; 67]

70 [66; 75]

71[64; 78]

70 [64; 76]

0.01

0.02

0.6

Male n (%)

21 (70)

19 (73)

11 (73)

8 (73)

0.8

0.8

1

Site n (%)

    

0.7

0.8

0.3

 - Cervical

3 (10)

3 (12)

1 (7)

2 (18)

   

 - Thoracic

7 (23)

7 (27)

3 (20)

4 (36)

  

 - Lumbar

18 (60)

16 (62)

11 (73)

5 (45)

  

Symptoms for more than 15 days n (%)

18 (60)

23 (88)

13 (87)

10 (91)

0.01

0.07

0.7

Duration (d) of hospitalization (median [95% CI])

28 [23.4;. 32.6]

21.5 [16.5; 26.4]

23.6 [15.8; 31.4]

18.5 [12.4; 24.7]

0.05

0.3

0.3

Temperature > 38 °C n (%)

15 (50)

5 (19)

5 (33)

0 (0)

0.01

0.3

0.05

Presence of risk factors n (%)

14 (47)

15 (58)

9 (60)

6 (55)

0.4

0.4

0.8

Cancer n (%)

0 (0)

4 (15)

3(20)

1 (9)

0.04

0.03

0.6

Diabetes n (%)

9 (30)

8 (31)

5 (33)

3 (27)

0.9

0.8

1

Entry site

 -Cutaneous n (%)

9 (30)

6 (23)

2 (13)

4 (36)

0.5

0.3

0.13

 -Catheter n (%)

1 (3)

5 (19)

3 (20)

2(18)

0.08

0.1

1

Blood cultures n (%)

20 (71)

13 (50)

12 (80)

1 (9)

0.1

0.5

0.001

Percutaneous needle biopsy made n (%)

11 (37)

19 (73)

9 (60)

10 (90)

0.008

0.1

0.07

Positive percutaneous needle biopsy n (%)

9 (82)

16 (84)

7 (78)

9 (90)

0.8

0.8

0.46

Leukocytes (G/L) (mean [95% CI])

9.9 [8.4; 11.4]

7.6 [6.6; 8.6]

8.3 [6.8; 9.7]

6.7 [5.2; 8.3]

0.01

0.5

0.1

PMN (G/L) (mean [95% CI])

7.5 [6.0; 9.0]

5.6 [4.6; 6.6]

6.3 [4.9; 7.7]

4.6 [3.2; 6.0]

0.04

0.1

0.07

ESR < 30 at 1 h n (%)

0 (0)

5 (23)

2(15)

3(33)

0.01

0.1

0.3

CRP > 10 mg/L n (%)

30 (100)

20 (77)

12(80)

8(73)

0.005

0.02

0.6

Antibiotic therapy duration (d) (median [95% CI])

91.5 [84.4; 98.7]

82.6 [74.5; 90.6]

75.6 [63.7; 87.5]

93.0 [86.2; 99.8]

0.1

0.05

0.09

Sensitivity to methicillin n (%)

24(80)

16 (61)

10(67)

6(55)

0.1

0.2

0.7

  1. PMN polymorphonuclear leucocytes, ESR erythrocyte sedimentation rate, CRP C-reactive protein