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Table 3 Statistically significant spatio-temporal clusters of A(H7N9) human infections in China identified by use of the space-time permutation scan test with 5-days scanning unit (phase II)

From: Spatio-temporal pattern analysis for evaluation of the spread of human infections with avian influenza A(H7N9) virus in China, 2013–2014

Cluster

Most likely cluster

Secondary cluster 2

Secondary cluster 3

Location

Ningbo, Shaoxing, Jiaxing, Zhuji, Hangzhou, Shanghai, Yiwu, Huzhou, Suzhou, Taizhou

Fuyang, Lu’an, Hefei, Xuzhou, Anqing, Tongling, Ma’anshan, Xuancheng, Nanjing, Huaian, Zhenjiang, Taian, Taizhou, Yancheng, Changzhou, Wuxi, Huangshan, Leping

Zhaoqing, Foshan, Jiangmen, Guangzhou

Province or region

Zhejiang, Jiangsu, Shanghai

Anhui, Jiangsu, Shandong, Jiangxi

Guangdong

Coordinates

29.86 N, 121.56 E

32.89 N, 115.81 E

23.06 N, 112.45 E

Radius (km)

194.90 km

453.14 km

80.49 km

Time frame

2014 1/12–1/31

2014 4/22–5/31

2014 2/16–3/2

Duration (days)

19

39

14

Oa

61

14

19

Eb

33.80

3.58

6.53

O / Ec

1.80

3.91

2.91

LLRd / Test statistic

10.292886

8.856121

8.095875

P-valuee

0.0016

0.011

0.028

  1. aNumber of cases observed per cluster
  2. bNumber of cases expected per cluster
  3. cObserved / Expected, Observed-to-expected ratio
  4. dLog Likelihood ratio
  5. eStatistical significance was evaluated using Monte Carlo hypothesis testing