Table 3 Study Characteristics of rapid-diagnostic tests (RDTs) or laboratory-based immunoassays (EIA) against nucleic-acid test reference standards [RDT/EIA vs NAT]
Study [author, year] | Location [country, city] | Sample size, n | Study design | Setting | Sample | Test under evaluation [type, brand] | Reference test [type, brand] |
|---|---|---|---|---|---|---|---|
Ansari, 2007 [51] | Iran, Urumieh | 240 | CC | Hospital patients | S | RDT, ACON RDT, Atlas RDT, Blue Cross RDT, Cortez RDT, DIMA RDT, Intec | qPCR |
Nna, 2014 [52] | Nigeria | 113 | CS | Blood donors (repeat) – all were HIV negative | P | RDT, ACON | Nested PCR; qPCR for positive |
Seremba, 2010 [53] | Uganda | 157 | CS - CSQ | Hospital patients (emergency medical ward), including HIV+ (83) and HIV- (74). | S | RDT, Cortez EIA, ADVIA | PCR |
Khadem-Ansari, 2014 [54] | Iran, Urumieh | 350 | CS – CSQ? | Hospital patients - referred as? HBV | S | ChLIA, Liaison | Rt-PCR |
Lukhwareni, 2009 [56] | South Africa | 192 | CC | HIV cohort - pre ART | S | ChLIA, Elecsys | qPCR |
Mphahlele, 2006 [57] | South Africa | 295 | CC | Hospital patients, HIV+ (167) and HIV- (128) | S | EIA, AxSYM | Nested PCR |
Olinger, 2007 [55] | Nigeria, Ibadan | 200 | CS | Hospital patients - Liver disease, HIV | S | MEIA, AxSYM v2 ChLIA, Elecsys ELFA, VIDAS Ultra | rtPCR and nested PCR |