Table 3 Mutations in PZA-susceptible MDR-TB isolates within pncA gene
Locus | Position of nucleotide | Nucleotide substitution | Position of amino acid | Amino acid substitution | No. of isolates |
|---|---|---|---|---|---|
pncA | 184 | CCG → ACG | 62 | Pro → Thr | 1 |
185 | CCG → CAG | 62 | Pro → Gln | 1 | |
200 | TCG → TGG | 67 | Ser → Trp | 1 | |
461 | AGG → AAG | 154 | Arg → Lys | 1 | |
Total | 4 | ||||