From: Predictors of unsuccessful interim treatment outcomes of multidrug resistant tuberculosis patients
Independent Variable* | Interim Treatment outcomes | B | S.E | p-value | (OR) 95% CI | |
---|---|---|---|---|---|---|
Unsuccessful (n = 32) | Successful (n = 48) | |||||
Age 25–34 (years) | ||||||
 No | 21 | 42 |  |  |  | 1 |
 Yes | 11 | 6 | 1.299 | 0.574 | .024 | 3.667 (1.191, 11.285) |
Weight†‡ | – | – | −0.027 | 0.020 | .187 | 0.974 (0.936, 1.013) |
Hb level‡ | ||||||
 Normal | 6 | 17 |  |  |  | 1 |
 Below normal | 26 | 31 | 0.866 | 0.544 | .112 | 2.376 (0.818, 6.905) |
Creatinine level‡ | ||||||
 Normal | 19 | 42 |  |  |  | 1 |
 Above normal | 11 | 6 | 1.399 | 0.578 | .015 | 4.053 (1.306, 12.580) |
Previous TB episodes†| – | – | 0.456 | 0.315 | .148 | 1.577 (0.850, 2.927) |
Months of sickness with TB | ||||||
  < 12 | 21 | 24 |  |  |  | 1 |
  ≥ 12 | 11 | 24 | −0.647 | 0.471 | .170 | 0.524 (0.208, 1.319) |
Previous TB treatment outcome failed | ||||||
 No | 30 | 40 |  |  |  | 1 |
 Yes | 2 | 8 | −1.099 | 0.827 | .184 | 0.333 (0.066, 1.685) |
History of streptomycin use | ||||||
 No | 15 | 37 |  |  |  | 1 |
 Yes | 17 | 11 | 1.338 | 0.493 | .007 | 3.812 (1.449, 10.026) |
Number of first line drugs with resistance¶ | ||||||
  < 4 | 11 | 8 |  |  |  | 1 |
  ≥ 4 | 14 | 22 | −0.770 | 0.577 | .182 | 0.463 (0.149, 1.434) |
Ofloxacin resistance | ||||||
 Present | 14 | 35 |  |  |  | 1 |
 Absent | 18 | 13 | 1.242 | 0.482 | .010 | 3.462 (1.345, 8.906) |
Sputum grading‡¶ | ||||||
 Low | 17 | 35 |  |  |  | 1 |
 High | 10 | 9 | 0.827 | 0.546 | .130 | 2.288 (0.784, 6.675) |
Positive culture after two months of treatment | ||||||
 No | 11 | 40 |  |  |  | 1 |
 Yes | 21 | 8 | 2.256 | 0.537 | < 0.01 | 9.545 (3.331, 27.354) |