Predictive implications of albumin and C-reactive protein for progression to pneumonia and poor prognosis in Stenotrophomonas maltophilia bacteremia following allogeneic hematopoietic stem cell transplantation

Table 3 Details of 9 patients with low albumin and high CRP

No.	Age	Primary disease	Stem cell source	Conditioning	Duration from transplantation to infection (days)	Engraftment	CRP (mg/dl)	Albumin (g/dl)	Severe sepsis or septic shock	Initial source of infection	Subsequent progression to pneumonia (days)	Treatment	Survival (days)
1	32	AML	uBM	BU+CY+TLI	124	Yes	11.6	1.9	-	Sources unknown	Yes (1)	MINO	12
2	58	AML	CB	Flu+Mel+TBI	26	No	14.4	2.3	Severe	Pneumonia		-	2
3	54	AML	CB	CA+CY+TBI	15	Yes	18.5	2.5	Severe	Sources unknown	Yes (5)	MINO	7
4	70	CMLBC	CB	Flu+Mel+TBI	20	No	40.8	2.9	Severe	Pneumonia		CPFX	2
5	69	AML	uBM	Flu+Mel+TBI	11	Yes	19.8	2.6	Shock	Pneumonia		-	2
6	64	PMF	uBM	Flu+Mel+TBI	34	No	25.3	1.6	Severe	Pneumonia		CPFX	2
7	57	FL	uPB	Flu+CY+TBI	10	No	15.9	2.4	Shock	Sources unknown	Yes (8)	CPFX+MINO	10
8	30	AML	uBM	CY+TBI	373	Yes	23	1.6	Shock	CLABSI	Yes (1)	CPFX+MINO→ST+MINO	2
9	56	AML	uBM	Flu+BU+TBI	17	No	17.8	1.6	Severe	Pneumonia and cellulitis		TGC→ST+TGC	32

Abbreviations: AML acute myeloid leukemia, CMLBC chronic myeloid leukemia blast crisis, PMF primary myelofibrosis, FL follicular lymphoma, uBM unrelated-bone marrow, CB cord blood, uPB unrelated-peripheral blood, BU busulfan, CY cyclophosphamide, TLI total lymphoid irradiation, Flu fludarabine, Mel melphalan, TBI total body irradiation, CRP c-reactive protein, CLABSI central-line associated blood stream infection, MINO minocycline, CPFX ciprofloxacin, ST trimethoprim-sulfamethoxazole, TGC tigecycline

ISSN: 1471-2334