|
No.
|
Age
|
Primary disease
|
Stem cell source
|
Conditioning
|
Duration from transplantation to infection (days)
|
Engraftment
|
CRP (mg/dl)
|
Albumin (g/dl)
|
Severe sepsis or septic shock
|
Initial source of infection
|
Subsequent progression to pneumonia (days)
|
Treatment
|
Survival (days)
|
|---|
|
1
|
32
|
AML
|
uBM
|
BU+CY+TLI
|
124
|
Yes
|
11.6
|
1.9
|
-
|
Sources unknown
|
Yes (1)
|
MINO
|
12
|
|
2
|
58
|
AML
|
CB
|
Flu+Mel+TBI
|
26
|
No
|
14.4
|
2.3
|
Severe
|
Pneumonia
| |
-
|
2
|
|
3
|
54
|
AML
|
CB
|
CA+CY+TBI
|
15
|
Yes
|
18.5
|
2.5
|
Severe
|
Sources unknown
|
Yes (5)
|
MINO
|
7
|
|
4
|
70
|
CMLBC
|
CB
|
Flu+Mel+TBI
|
20
|
No
|
40.8
|
2.9
|
Severe
|
Pneumonia
| |
CPFX
|
2
|
|
5
|
69
|
AML
|
uBM
|
Flu+Mel+TBI
|
11
|
Yes
|
19.8
|
2.6
|
Shock
|
Pneumonia
| |
-
|
2
|
|
6
|
64
|
PMF
|
uBM
|
Flu+Mel+TBI
|
34
|
No
|
25.3
|
1.6
|
Severe
|
Pneumonia
| |
CPFX
|
2
|
|
7
|
57
|
FL
|
uPB
|
Flu+CY+TBI
|
10
|
No
|
15.9
|
2.4
|
Shock
|
Sources unknown
|
Yes (8)
|
CPFX+MINO
|
10
|
|
8
|
30
|
AML
|
uBM
|
CY+TBI
|
373
|
Yes
|
23
|
1.6
|
Shock
|
CLABSI
|
Yes (1)
|
CPFX+MINO→ST+MINO
|
2
|
|
9
|
56
|
AML
|
uBM
|
Flu+BU+TBI
|
17
|
No
|
17.8
|
1.6
|
Severe
|
Pneumonia and cellulitis
| |
TGC→ST+TGC
|
32
|
-
Abbreviations: AML acute myeloid leukemia, CMLBC chronic myeloid leukemia blast crisis, PMF primary myelofibrosis, FL follicular lymphoma, uBM unrelated-bone marrow, CB cord blood, uPB unrelated-peripheral blood, BU busulfan, CY cyclophosphamide, TLI total lymphoid irradiation, Flu fludarabine, Mel melphalan, TBI total body irradiation, CRP c-reactive protein, CLABSI central-line associated blood stream infection, MINO minocycline, CPFX ciprofloxacin, ST trimethoprim-sulfamethoxazole, TGC tigecycline
