Shifting trends in bacteriology and antimicrobial resistance among gastrointestinal fistula patients in China: an eight-year review in a tertiary-care hospital

Table 3 Antimicrobial resistance of Klebsiella pneumonia isolates to the tested antibiotics

Resistance rate (%)
Isolate/Antibiotics	2008–2011	2012–2015	Total	P for Trend Test
All Klebsiella pneumonia
AMK	40.91	36.11	37.93	0.605
SAM	97.14	85.14	88.99	0.061
TZP	75.00	58.11	64.75	0.056
CTT	60.61	54.79	56.60	0.576
CAZ	89.80	78.38	82.93	0.099
FEP	75.00	67.57	70.49	0.379
IPM	65.31	56.76	60.16	0.343
CIP	74.29	75.68	75.23	0.875
ESBL+
AMK	33.33	7.41	16.67	0.031
SAM	100.00	89.29	92.11	0.281
TZP	55.56	17.86	32.61	0.008
CTT	12.50	14.81	14.29	0.869
CAZ	94.44	71.43	80.43	0.055
FEP	83.33	53.57	65.22	0.039
IPM	38.89	14.29	23.91	0.056
CIP	50.00	71.43	65.79	0.220
ESBL-
AMK	40.91	53.33	49.25	0.339
SAM	94.44	82.61	85.94	0.221
TZP	86.36	82.61	83.82	0.694
CTT	88.89	78.26	81.25	0.327
CAZ	82.61	82.61	82.61	–
FEP	72.73	76.09	75.00	0.765
PM	78.26	82.61	81.16	0.663
CIP	83.33	78.26	79.69	0.650
Not all tested antibiotics are listed

AMK Amikacin, SAM Ampicillin/Sulbactam, CAZ Ceftazidime, FEP Cefepime, CTT Cefotetan, IPM Imipenem, TZP Piperacillin-Tazobactam, CIP Ciprofloxacin
Data in boldface reflected p values < 0.05

ISSN: 1471-2334