Correlates of isoniazid preventive therapy failure in child household contacts with infectious tuberculosis in high burden settings in Nairobi, Kenya – a cohort study

Table 2 Baseline characteristics of contacts completing IPT follow-up

Characteristic		(N = 368) N (%)^a
Contact’s age (months)	≤ 24 months	208(56.5)
Contact’s age (months)	> 24 months	168(43.5)
Gender	Male	189(51.1)
Gender	Female	179(48.9)
Birth order	1st	154(41.8)
	2nd	126(34.2)
	≥ 3rd	88(23.9)
Birth weight (grams)	< 2500 g	13(2.7)
	2500–4000 g	316(85.9)
	> 4000 g	39(11.1)
Morbidity patterns	≥ 1 out-patient visit in 1 yr	50(13.6)
Morbidity patterns	≥ 1 hospital admission in 1 yr	41(11.1)
Breast feeding status	Exclusive breastfeeding	44(12.0)
	Currently breastfeeding	189(34.2)
	Not breastfeeding	135(36.6)
Weaning age (months)	Not yet weaned	44(12.0)
	< 4 months	128(34.7)
	4–6 months	196(53.3)
Nutrition status^b	Weight faltering/underweight	43(11.7)
Nutrition status^b	Normal (> − 2 z-score)	325(89.9)
BCG vaccination	Scar present	300(91.5)
BCG vaccination	Absent scar	68(18.5)
Visiting social places^c	Yes	293(79.3)
Visiting social places^c	No	75(20.7)
TB suggestive symptoms ^d	Yes	126(34.2)
TB suggestive symptoms ^d	No	242(66.8)
Baseline TST reaction	Positive	76(20.6)
Baseline TST reaction	Negative	292(79.4)
HIV DNA PCR	Positive	25(6.7)
HIV DNA PCR	Negative/not done	343(93.3)

^aFrequencies are presented in absolute number and percentages, ^b malnutrition was present in those with any weight faltering on their growth charts and those who had under-nutrition <80%, ^c Social places visited included churches, mosques, market places, or schools. ^d TB suggestive symptoms included those with cough ≥2 weeks, fever ≥2 weeks, weight loss, fatigue, reduced play, or any swellings. BCG Bacille Calmette-Guerin vaccine, HIV Human Immune Deficiency virus, DNA Deoxyribonucleic acid, PCR polymerase chain reaction, TB tuberculosis, TST tuberculin skin test

ISSN: 1471-2334