Fig. 1

Subjects’ enrollment and participants. a Smear + = Sputum smear positive for acid alcohol fast bacilli, b Accepted to give the child isoniazid prophylaxis, c Contacts recruited are those that were eligible and consented to participate, d Contacts defaulting IPT are those that stopped the taking isoniazid, those that discontinued the 1 year follow-up program before endpoint, and those that transferred out of the study sites. TB tuberculosis, IPT Isoniazid preventive therapy