| |
Univariate results
|
Multivariate results
|
|---|
|
OR
|
95% CI
|
p-value
|
OR
|
95% CI
|
p-value
|
|---|
|
Age ≥ 40 years
|
0.35
|
0.15–0.82
|
0.0144
|
0.35
|
0.13–0.92
|
0.0324
|
|
Body weight < 65 kg
|
0.71
|
0.33–1.53
|
0.3864
|
1.02
|
0.41–2.57
|
0.9705
|
|
Sex (Male)
|
3.95
|
0.90–27.5
|
0.0693
|
3.84
|
0.73–30.5
|
0.1175
|
|
HIV-1-RNA level at the time of sampling (< 50 copies/mL)
|
0.98
|
0.04–25.2
|
0.9894
|
0.53
|
0.02–15.7
|
0.6786
|
|
Number of UGT1A1*6 alleles
|
|
0
|
1
| | |
1
| | |
|
1
|
2.52
|
1.02–6.46
|
0.0434
|
3.33
|
1.24–9.51
|
0.0164
|
|
2
|
4.4 × 107
|
5.21-∞
|
0.0003
|
5.9 × 107
|
6.90-∞
|
0.0001
|
|
Number of UGT1A1*28 alleles
|
|
0
|
1
| | |
1
| | |
|
1
|
2.03
|
0.78–5.57
|
0.1476
|
3.61
|
1.24–11.5
|
0.0184
|
|
2
|
2.32
|
0.21–50.9
|
0.4862
|
4.01
|
0.33–93.4
|
0.2669
|
-
OR odds ratio, CI confidence interval, UGT1A1 uridine diphosphate-glucuronosyltransferase 1A1, HIV human immunodeficiency virus
