Genotype | −/− | −/*28 | −/*6 | *28/*28 | *6/*28 | *6/*6 | p-value |
---|---|---|---|---|---|---|---|
Participants (n, %) | 51 (48%) | 18 (17%) | 23 (21%) | 3 (3%) | 4 (4%) | 8 (7%) | Â |
Age (year), median [IQR] | 44 [39–51] | 43 [39–53] | 42 [38–45] | 42 [41–43] | 46 [44–51] | 44 [38–50] | 0.8351 |
Males (n, %) | 48 (94%) | 15 (83%) | 20 (87%) | 3 (100%) | 4 (100%) | 8 (100%) | 0.5445 |
Body weight (kg), median [IQR] | 65 [58–72] | 66 [58–72] | 67 [61–74] | 64 [61–77] | 55 [51–59] | 68 [60–73] | 0.4805 |
Treatment naïve (n, %) | 9 (18%) | 5 (28%) | 9 (39%) | 0 (0%) | 1 (25%) | 2 (25%) | 0.4084 |
CD4 cell count (cells/mL), median at the time of sampling [IQR] | 486 [329–616] | 431 [366–552] | 378 [331–546] | 434 [406–667] | 500 [405–628] | 540 [485–583] | 0.5838 |
Participants with <50 HIV-1-RNA levels at the time of sampling (n, %) | 50 (98%) | 18 (100%) | 22 (96%) | 3 (100%) | 4 (100%) | 8 (100%) | 0.9241 |
CD4 cell count (cells/mL), median at 24 weeks [IQR] | 511 [336–603] | 464 [402–623] | 424 [335–528] | 638 [507–819] | 464 [402–563] | 642 [584–669] | 0.1145 |
Participants with <50 HIV-1-RNA levels at 24Â weeks (n, %) | 51 (100%) | 18 (100%) | 23 (100%) | 3 (100%) | 4 (100%) | 8 (100%) | 1.000 |
Use of antiretroviral agents (n, %) | |||||||
 Tenofovir disoproxil fumarate | 26 (51%) | 9 (50%) | 12 (52%) | 2 (67%) | 4 (100%) | 4 (57%) | 0.5559 |
 Abacavir sulfate | 25 (49%) | 9 (50%) | 11 (48%) | 1 (33%) | 0 (0%) | 3 (43%) | 0.4298 |
 Rilpivirine hydrochloride | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (13%) | 0.0286 |
Duration of DTG treatment (days), median [IQR] | 111 [63–169] | 112 [78–215] | 77 [60–117] | 67 [62–111] | 67 [44–113] | 68 [30–94] | 0.3474 |
Food consumption | Â | Â | Â | Â | Â | Â | 0.2698 |
 Fasting | 16 (31%) | 9 (50%) | 8 (35%) | 1 (33%) | 3 (75%) | 5 (63%) |  |
 Light meal | 35 (69%) | 9 (50%) | 15 (65%) | 2 (67%) | 1 (25%) | 3 (37%) |  |
HBV infection (n, %) | 4 (8%) | 1 (6%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (13%) | 0.7028 |
HCV infection (n, %) | 2 (4%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 1.0000 |