Table 1 Bivariate analysis of characteristics associated with treatment failure and reinfection
Characteristic | Serological cure/Serofast | Treatment failure/Reinfection | OR (95% CI) | p-value |
|---|---|---|---|---|
Age | ||||
< 25 | 100 | 9 | – | |
25-35 | 154 | 22 | 1.26 (0.73, 2.30) | 0.42 |
> 35 | 200 | 25 | 0.78 (0.47, 1.29) | 0.33 |
Gender | ||||
Male | 285 | 29 | – | |
Female | 169 | 27 | 1.57 (0.89, 2.74) | 0.11 |
Syphilis stage | ||||
primary | 61 | 3 | – | |
secondary | 123 | 19 | 3.14 (1.02, 13.73) | 0.07 |
latent | 270 | 34 | 2.56 (0.88, 10.87) | 0.13 |
Baseline titer | ||||
< 1:32 | 289 | 27 | – | |
≥ 1:32 | 165 | 29 | 1.88 (1.07, 3.30) | 0.02 |
HIV status | ||||
Positive | 50 | 11 | 1.98 (0.92, 3.95) | 0.06 |
Negative | 404 | 45 | – | |
Sexual orientation | ||||
Non-MSM | 390 | 44 | – | |
MSM | 64 | 12 | 1.66 (0.80, 3.22) | 0.15 |
History of STIsa | ||||
No | 398 | 52 | – | |
Yes | 56 | 4 | 0.54 (0.16, 1.40) | 0.26 |
No. of sex partners | ||||
0-2 | 352 | 44 | – | |
3-5 | 62 | 5 | 0.64 (0.21, 1.55) | 0.37 |
6-10 | 25 | 4 | 1.28 (0.36, 3.49) | 0.66 |
> 10 | 15 | 3 | 1.60 (0.36, 5.09) | 0.47 |
Frequency of condom use | ||||
Never | 272 | 38 | – | |
Sometimes | 88 | 11 | 0.89 (0.42, 1.77) | 0.76 |
Always | 94 | 7 | 0.53 (0.22, 1.16) | 0.14 |