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Table 6 Main S. pneumoniae serotypes isolated from patients with invasive pneumococcal disease cared for in Regional Health Care Network 13, according to age, from 1998 to 2013

From: Distribution of Streptococcus pneumoniae serotypes in the northeast macro-region of São Paulo state/Brazil after the introduction of conjugate vaccine

Serotype   Age group (years) Total p value
< 1 n = 112 1˫ 2
n = 88
2˫5
n = 98
Subtotal < 5
n = 298
5˫20
n = 110
20˫60
n = 256
≥60
n = 107
Subtotal ≥ 5
n = 473
n = 771  
no %* no %* no % no %* no %* no %* no %* no % no %  
14 37 33.0 36 40.9 38 38.8 111 37.2 8 7.3 15 5.9 7 6.5 30 6.3 141 18.3 <0.001
3 8 7.1 5 5.7 3 3.1 16 5.4 5 4.5 34 13.3 17 15.9 56 11.8 72 9.3 0.001
19F 3 2.7 1 1.1 5 5.1 9 3.0 11 10.0 13 5.1 9 8.4 33 7.0 42 5.4 0.005
1 3 2.7 2 2.3 11 11.2 16 5.4 16 14.5 7 2.7 3 2.8 26 5.5 42 5.4 <0.001
6A 10 8.9 3 3.4 8 8.2 21 7.0 7 6.4 9 3.5 2 1.9 18 3.8 39 5.1 0.079
6B 6 5.4 10 11.4 3 3.1 19 6.4 0 0.0 13 5.1 5 4.7 18 3.8 37 4.8 0.012
23F 4 3.6 5 5.7 2 2.0 11 3.7 6 5.5 12 4.7 7 6.5 25 5.3 36 4.7 0.696
9V 4 3.6 4 4.5 3 3.1 11 3.7 5 4.5 8 3.1 10 9.3 23 4.9 34 4.4 0.167
18C 6 5.4 4 4.5 6 6.1 16 5.4 8 7.3 5 2.0 3 2.8 16 3.4 32 4.2 0.174
19A 10 8.9 3 3.4 3 3.1 16 5.4 2 1.8 9 3.5 6 5.6 17 3.6 33 4.3 0.123
12F 1 0.9 1 1.1 1 1.0 3 1.0 4 3.6 15 5.9 4 3.7 23 4.9 26 3.4 0.074
4 0 0.0 0 0.0 2 2.0 2 0.7 2 1.8 16 6.2 4 3.7 22 4.7 24 3.1 0.007
7F 2 1.8 2 2.3 1 1.0 5 1.7 3 2.7 9 3.5 3 2.8 15 3.2 20 2.6 0.825
5 2 1.8 3 3.4 1 1.0 6 2.0 3 2.7 6 2.3 0 0.0 9 1.9 15 1.9 0.531
11A 0 0.0 0 0.0 0 0.0 0 0.0 2 1.8 10 3.9 2 1.9 14 3.0 14 1.8 0.036
22F 1 0.9 0 0.0 1 1.0 2 0.7 1 0.9 7 2.7 3 2.8 11 2.3 13 1.7 0.404
8 1 0.9 0 0.0 0 0.0 1 0.3 0 0.0 9 3.5 1 0.9 10 2.1 11 1.4 0.027
9N 0 0.0 1 1.1 0 0.0 1 0.3 3 2.7 5 2.0 1 0.9 9 1.9 10 1.3 0.357
  1. %* refers to the total number of cases in each age group - 25 patients were excluded for lack of information regarding the age range
  2. p values in bold are significant