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Table 6 Main S. pneumoniae serotypes isolated from patients with invasive pneumococcal disease cared for in Regional Health Care Network 13, according to age, from 1998 to 2013

From: Distribution of Streptococcus pneumoniae serotypes in the northeast macro-region of São Paulo state/Brazil after the introduction of conjugate vaccine

Serotype

 

Age group (years)

Total

p value

< 1 n = 112

1˫ 2

n = 88

2˫5

n = 98

Subtotal < 5

n = 298

5˫20

n = 110

20˫60

n = 256

≥60

n = 107

Subtotal ≥ 5

n = 473

n = 771

 

no

%*

no

%*

no

%

no

%*

no

%*

no

%*

no

%*

no

%

no

%

 

14

37

33.0

36

40.9

38

38.8

111

37.2

8

7.3

15

5.9

7

6.5

30

6.3

141

18.3

<0.001

3

8

7.1

5

5.7

3

3.1

16

5.4

5

4.5

34

13.3

17

15.9

56

11.8

72

9.3

0.001

19F

3

2.7

1

1.1

5

5.1

9

3.0

11

10.0

13

5.1

9

8.4

33

7.0

42

5.4

0.005

1

3

2.7

2

2.3

11

11.2

16

5.4

16

14.5

7

2.7

3

2.8

26

5.5

42

5.4

<0.001

6A

10

8.9

3

3.4

8

8.2

21

7.0

7

6.4

9

3.5

2

1.9

18

3.8

39

5.1

0.079

6B

6

5.4

10

11.4

3

3.1

19

6.4

0

0.0

13

5.1

5

4.7

18

3.8

37

4.8

0.012

23F

4

3.6

5

5.7

2

2.0

11

3.7

6

5.5

12

4.7

7

6.5

25

5.3

36

4.7

0.696

9V

4

3.6

4

4.5

3

3.1

11

3.7

5

4.5

8

3.1

10

9.3

23

4.9

34

4.4

0.167

18C

6

5.4

4

4.5

6

6.1

16

5.4

8

7.3

5

2.0

3

2.8

16

3.4

32

4.2

0.174

19A

10

8.9

3

3.4

3

3.1

16

5.4

2

1.8

9

3.5

6

5.6

17

3.6

33

4.3

0.123

12F

1

0.9

1

1.1

1

1.0

3

1.0

4

3.6

15

5.9

4

3.7

23

4.9

26

3.4

0.074

4

0

0.0

0

0.0

2

2.0

2

0.7

2

1.8

16

6.2

4

3.7

22

4.7

24

3.1

0.007

7F

2

1.8

2

2.3

1

1.0

5

1.7

3

2.7

9

3.5

3

2.8

15

3.2

20

2.6

0.825

5

2

1.8

3

3.4

1

1.0

6

2.0

3

2.7

6

2.3

0

0.0

9

1.9

15

1.9

0.531

11A

0

0.0

0

0.0

0

0.0

0

0.0

2

1.8

10

3.9

2

1.9

14

3.0

14

1.8

0.036

22F

1

0.9

0

0.0

1

1.0

2

0.7

1

0.9

7

2.7

3

2.8

11

2.3

13

1.7

0.404

8

1

0.9

0

0.0

0

0.0

1

0.3

0

0.0

9

3.5

1

0.9

10

2.1

11

1.4

0.027

9N

0

0.0

1

1.1

0

0.0

1

0.3

3

2.7

5

2.0

1

0.9

9

1.9

10

1.3

0.357

  1. %* refers to the total number of cases in each age group - 25 patients were excluded for lack of information regarding the age range
  2. p values in bold are significant