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Table 3 Vaccine and non-vaccine serotypes of S. pneumoniae identified in patients with invasive pneumococcal disease cared for in Regional Health Care Network 13, according to the isolation period, 1998 to 2013

From: Distribution of Streptococcus pneumoniae serotypes in the northeast macro-region of São Paulo state/Brazil after the introduction of conjugate vaccine

Serotypes

Periods

Total

1998–2002

2003–2010

2011–2013

no

%*

no

%*

no

%*

no

%

PCV7

        

 14

45

20.3

94

19.6

6

6.3

145

18.2

 19F

15

6.8

28

5.8

3

3.2

46

5.8

 6B

7

3.2

27

5.6

4

4.2

38

4.8

 23F

8

3.6

29

6.1

0

0.0

37

4.6

 9V

6

2.7

25

5.2

3

3.2

34

4.3

 18C

13

5.9

15

3.1

5

5.3

33

4.1

 4

8

3.6

13

2.7

3

3.2

24

3.0

 Total PCV7

102

45.9

231

48.2

24

25.3

357

44.8

Included PCV10

        

 1

12

5.4

31

6.5

0

0.0

43

5.4

 7 F

7

3.2

12

2.5

2

2.1

21

2.6

 5

14

6.3

1

0.2

2

2.1

17

2.1

 Total PCV10

33

14.9

44

9.2

4

4.2

81

10.2

Included PCV13

        

 3

14

6.3

42

8.8

17

17.9

73

9.2

 6A

13

5.9

20

4.2

6

6.3

39

4.9

 19A

13

5.9

18

3.8

2

2.1

33

4.1

 Total PCV13

40

18.0

80

16.7

25

26.3

145

18.2

Non-vaccine

        

 12F

1

0.5

18

3.8

9

9.5

28

3.5

 11A

0

0.0

12

2.5

3

3.2

15

1.9

 22F

3

1.4

12

2.5

0

0.0

15

1.9

 8

2

0.9

5

1.0

5

5.3

12

1.5

 9N

1

0.5

6

1.3

3

3.2

10

1.3

 10A

3

1.4

5

1.0

1

1.1

9

1.1

 15C

2

0.9

3

0.6

4

4.2

9

1.1

 17F

3

1.4

5

1.0

0

0.0

8

1.0

 6C

1

0.5

3

0.6

4

4.2

8

1.0

 18A

4

1.8

3

0.6

0

0.0

7

0.9

 18B

2

0.9

5

1.0

0

0.0

7

0.9

 23B

1

0.5

5

1.0

0

0.0

6

0.8

 NT

3

1.4

3

0.6

0

0.0

6

0.8

 NR

0

0.0

2

0.4

0

0.0

2

0.3

 Othera

21

9.5

37

7.7

13

13.7

71

8.9

 Total non- vaccine

47

21.2

124

25.9

42

44.2

215

27.0

 Total

222

100.0

479

100.0

95

100.0

796

100.0

  1. %* refers to the total casos of IPDs in each period, Other aserotypes with less than 6 isolates
  2. NT Non-typable, NR Not carried out (unviable strain)
  3. PCV7 – valent pneumococcal conjugate vaccine
  4. PCV10–10-valent pneumococcal conjugate vaccine
  5. PCV13–13-valent pneumococcal conjugate vaccine