Table 7 Median markers levels in serum and saliva that were significantly different between the active TB group (TB), latent TB infection and uninfected (No TB infection) group
From: Suitability of saliva for Tuberculosis diagnosis: comparing with serum
Groups | PTB vs LTBI | PTB vs HE | LTBI vs HE | |
|---|---|---|---|---|
Marker | IL-6 Serum | VEGF Serum | IFN-γ saliva | |
PTB Median pg/ml | 33.11 (12.9–60.3) | 224.6 (93.2–654.9) | 0 (0.0–15.6) | |
LTBI (median pg/ml) | 7.6 (5.6–10.7) | 57.1 (0.0–230.3) | 0 (0–16.7) | |
Uninfected (median pg/ml) | 6.7 (4.3–8.7) | 69.8 (0.0–198.9) | 0.0 (0.0–0.0) | |
p-value | <0.0001 | 0.001 | 0.03 | 0.04 |
AUC | 0.85 | 0.71 | 0.65 | 0.66 |
Cut off | >36.4 | >573.8 | <0.47 | <0.47 |
Sensitivity | 46.15 | 28.21 | 88.9 | 88.9 |
Specificity | 97.44 | 97.44 | 41 | 43 |