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Table 5 Median levels of the most promising host markers detected in serum samples from patients with active TB group (TB) or ORD group and accuracies in the diagnosis of TB disease

From: Suitability of saliva for Tuberculosis diagnosis: comparing with serum

Groups

TB Vs ORD

Marker

IL-6 Serum

VEGF Serum

ORD (median pg/ml)

6.9 (5.6–9.9)

57.06 (0–208.6)

PTB (Median pg/ml)

33.11 (12.9–60.2)

224.6 (93.2–654.9)

p-value

<0.0001

0.001

AUC

0.85

0.71

Cut off

>36.4

>573.8

Sensitivity

46.15

28.21

Specificity

97.44

97.44

  1. Table 5: Shown are the median and ranges (in parenthesis) levels of serum markers that were significantly different between the TB patients and the group with other respiratory diseases (ORD) and area under the curve (AUC) showing the diagnostic performance of the markers