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Table 4 Median levels of markers were significantly different between saliva and serum for all participants

From: Suitability of saliva for Tuberculosis diagnosis: comparing with serum

Marker

Median (pg/ml) Saliva

Median (pg/ml) serum

p-value

IL-5

3.6 (2.7–4.7)

1.6 (0.6–2.1)

<0.0001

IL-6

4.8 (2.1–5.4)

6.9 (5.6–9.9)

<0.0001

G-CSF

0.0 (0.0–53.2)

72.5 (49.1–97.1)

<0.0001

GM-CSF

282.2 (36.3–405.5)

0.0 (0.0–0.0)

<0.0001

MIP-1a

1.9 (1.3–2.3)

7.39 (3.9–35.8)

<0.0001

MIP-1b

0.0 (0.0–0.0)

201.9 (127.5–297.3)

<0.0001

VEGF

1368 (550.5–2020)

57.1 (0–208.6)

<0.0001

TNF-a

0.0 (0.0–4.3)

12.7 (8.5–19.1)

<0.0001

IFNg

0.0 (0.0–7.7)

15.3 (10.4–52.9)

0.0003

  1. Table 4: Shown are the marker levels that are significantly different (median levels and ranges (in parenthesis) in serum compared to saliva in only participants with other respiratory diseases with Area Under the ROC curve ranging between 0.74–1