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Table 3 Median levels of markers were significantly different between saliva and serum for all active pulmonary TB participants

From: Suitability of saliva for Tuberculosis diagnosis: comparing with serum

Marker

Median (pg/ml) Saliva

Median (pg/ml) serum

p-value

IL-5

3.7 (2.7–4.7)

1.6 (0.6–2.7)

<0.0001

IL-6

5.1 (2.4–9.5)

33.1 (12.9–60.3)

<0.0001

G-CSF

0.0 (0.0–40.5)

76.1 (53.2–123.0)

<0.0001

GM-CSF

257.9 (77.9–428.9)

0.0 (0.0–0.0)

<0.0001

MIP-1a

1.9 (1.1–2.6)

6.41 (4.2–35.6)

<0.0001

MIP-1b

0.0 (0.0–0.0)

178.1 (98.7–245.8)

<0.0001

VEGF

1486 (104–1960)

224.6 (93.2–654.9)

<0.0001

TNF-a

0.0 (0.0–8.5)

19.6 (7.4--26.6)

<0.0001

IFNg

0.0 (0.0–15.6)

43.3 (0.94–74.3)

0.0003

  1. Table 3: Shown are the marker levels that are significantly different (median levels and inter quartile ranges (in parenthesis) in serum compared to saliva in only active pulmonary TB participants with Area Under the ROC curve ranging between 0.73–0.97