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Table 2 Median levels of host markers were significantly different between saliva and serum samples from all participants, regardless of TB disease status

From: Suitability of saliva for Tuberculosis diagnosis: comparing with serum

Marker

Median (pg/ml) Saliva

Median (pg/ml) serum

p-value

IL-2

0.0 (0.0–46.2)

0.0 (0.0–121.0)

0.03

IL-5

1.6 (0.0–25.0)

3.6 (0.6–27.5)

<0.0001

IL-6

4.9 (2.4–7.8)

10.17 (6.5–36.3)

<0.0001

G-CSF

0.0 (0.0–50.1)

72.5 (52.2–103.7)

<0.0001

GM-CSF

261.2 (40.4–409.1)

0.0 (0.0–0.0)

<0.0001

MIP-1a

1.9 (1.1–2.5)

6.7 (4.2–35.6)

<0.0001

MIP-1b

0.0 (0.0–0.0)

187.1 (114.4–260.4)

<0.0001

VEGF

1467.2 (678.4–1975)

154 (0.0–322.2)

<0.0001

TNF-a

0.0 (0.0–4.8)

14.8 (8.2–22.5)

<0.0001

IFNg

0.0 (0.0–13.1

44.3 (8.1–60.6)

0.0003

  1. Table 2: Shown are the median marker levels (inter quartile ranges in parenthesis) for markers that were significantly different in serum compared to saliva in all participants, regardless of TB disease status